妊娠期高血压的脑胎盘比及其对新生儿体重的影响

M. Alalfy, A. Okasha, Omar Abdalfatah
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引用次数: 1

摘要

背景:妊娠是一个生理过程,涉及血管系统反应性的变化,通过激素和其他信号直接或间接地影响胎盘发育,这些信号对胎儿系统内的正常血流速率至关重要。利用超声指标预测胎儿结局被认为是一种无创的有价值的方案来管理妊娠期高血压疾病的病例。胎儿体重是产科医生和围产期医生面临的关键问题之一,本研究的目的是:确定在妊娠期高血压病例中,脑胎盘比在新生儿体重预测中的价值。患者与方法:采用前瞻性横断面观察研究,纳入在Algezeera医院产前保健门诊就诊的100名孕妇,其中50名为妊娠期高血压患者,50名为正常对照组。超声检查结合常规胎儿生物测量、大脑中动脉(MCA)、脐动脉(UA)多普勒指数进行评估。结果:对照组UA PI、MCA PI、CPR、胎儿体重、出生体重均高于妊高征研究组,差异有统计学意义(p值<0.001)。结论:脑胎盘比是一种很有前途的胎儿和新生儿体重超声指标,有助于预测新生儿健康状况和妊娠期高血压患者的临床预后。
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Cerebroplacental ratio in gestational hypertension and its impact on neonatal weight
Background: Pregnancy a physiological process that involves changes in vascular system responsiveness that affects the placental development in direct and indirect methods by hormonal and other signals that are critical in normal blood flow rates within the fetal system. Predicting fetal outcome using sonographic indices is considered a noninvasive valuable protocol to manage cases with hypertensive disorders with pregnancy. Fetal weight is one of the critical issues faced by obstetricians and perinatologists Aim of the study: to determine the value of cerebro placental ratio in predictability of neonatal weight in cases of gestational hypertension. Patients and Methods: A prospective observational cross sectional study that included 100 pregnant women, 50 ladies had gestational hypertension and 50 women as normal control group attending the antenatal care clinic of Algezeera hospital. Ultrasonographic assessment was carried out with evaluation of routine fetal biometry in addition to Middle cerebral artery (MCA), Umbilical artery (UA) Doppler indices. Results: UA PI, MCA PI, CPR, Fetal weight and birth weight were statistically significantly higher among the control research group in comparison to the hypertension with pregnancy research group (p values<0.001). Conclusion: Cerebroplacental ratio is a promising ultrasonographic marker for fetal and neonatal weight that could aid in prediction of neonatal wellbeing and clinical prognosis of hypertensive cases in pregnancy.
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