气相色谱-质谱-液-液萃取法检测血液和尿液中部分合成大麻素(ub - amb和AB-FUBINACA)

AM El-Essawy, Ahmed MA Shihata, Emad HA Mohamed
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引用次数: 0

摘要

近年来,各种类型的合成大麻素已广泛分布,并在世界大部分地区引起了社会和健康问题。合成大麻素是目前最大的一类新型精神活性物质。那些受法律管制的物质被新的受管制和不受管制的物质所取代。最近在年轻人中销售的一些合成大麻素是FUB-AMB和AB-FUBINACA。本研究对两例吸烟患者的血液和尿液进行了定量分析,其中,AB-FUB分别为0.06 ~ 0.03 ng/mL和1.7 ~ 2.9 ng/mL。
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Detection of some synthetic cannabinoids (FUB-AMB and AB-FUBINACA) in blood and urine using gas chromatography-mass spectrometry liquid–liquid extraction
has a binding affinity CB1 receptor that is four times greater than of THC and ten than Abstract In recent years, various types of synthetic cannabinoids have become widely distributed and are causing social and health problems in most parts of the world. Synthetic cannabinoids are currently the largest group of new psychoactive substances. Those that have been subjected to legal control are replaced by newer controlled and uncontrolled substances. Some of the most recent synthetic cannabinoids that have distributed on the market among youth are FUB-AMB and AB-FUBINACA. This study quantified blood and urine of two cases smoking tobacco mixed with AMB-FUB 0.06-0.03 ng/mL and 1.7-2.9 ng/mL AB-FUB in urine and blood respectively.
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