丝胶蛋白的提取及生物应用综述

A. Sarangi, S. Baral, H. Thatoi
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摘要

丝胶是丝绸工业的副产品。家蚕主要负责丝胶蛋白的合成。丝胶本质上是蛋白质,是可生物降解的。生丝的两种主要成分,即丝素和丝胶蛋白,必须通过脱胶过程从生丝中去除,使其具有光泽或光泽。丝胶及其营养价值在中国和日本已为人们所熟知。丝胶蛋白的许多用途如医药用途,纺织用途,化妆品用途在印度已经被探索但丝胶蛋白作为膳食补充剂的用途还没有被发现。印度已经生产了成吨的丝绸,脱胶后的水被当作废物利用。丝胶蛋白的纳米技术发现在生物医学和组织工程领域取得了最重要的进展,特别是考虑到天然产物在增强新药物配方和生物材料方面的应用。丝胶缀合纳米制剂是纳米技术工具应用于生物相容性、经济可行性和可生物降解化合物蓝图及其用作纳米药物的一个巨大例子。本文综述了丝胶蛋白在生物医学、食品添加剂以及丝胶蛋白纳米配方等领域的应用。
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Extraction and Biological Application of Silk Sericin: An Over View
The sericin is a byproduct which is obtained from silk industries. Mainly Bombyx mori is responsible for the synthesis of sericin. Sericin is proteinaceous in nature and is biodegradable. The two major components of silk i.e., fibroin and sericin have to be removed from raw silk to give it a luster or shine by degumming process. Silk sericin and its nutritive value has now been known to everyone in China and Japan. Many uses of sericin like pharmaceutical uses, textile -based uses, use in cosmetics has now been explored in India but the use of sericin as dietary supplement is not still discovered. Tons of silk has been produced in India and the degummed water goes as waste which can be used. Nanotechnological discoveries of sericin have given foremost advances in the field of biomedicine and tissue engineering, with special consideration the applications of a natural product for the enhancement of new pharmaceutical formulations and biomaterials. Sericin conjugated nano formulation are a vast example of nanotechnological tools applied to the blueprint of an biocompatible, economically viable, and biodegradable compound as well as its use as nanomedicine. The aim of this review is to highlight the application of sericin in different fields like in biomedical, food additives and the nano formulation of silk sericin.
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