F. Akinkunmi, S. Ajoseh, C. Fakorede, R. Abegunrin, W. Salami, Aminat K. Lawal, K. Akinyemi
{"title":"尼日利亚拉各斯沙门氏菌血液感染的流行和抗菌素耐药性。","authors":"F. Akinkunmi, S. Ajoseh, C. Fakorede, R. Abegunrin, W. Salami, Aminat K. Lawal, K. Akinyemi","doi":"10.52547/iem.9.1.1","DOIUrl":null,"url":null,"abstract":"(n=6, 10.91%), Proteus species (n=13, 23.64%), Serratia species (n=7, 12.73%), and Citrobacter species (n=2, 3.64%). In this study, the detection rate of Salmonella isolates in positive blood culture samples using qPCR and inv A gene primer set was 100%. Salmonella isolates were %100 resistant to ceftazidime, cefotaxime, and doripenem. Multidrug resistance (MDR) was observed in Salmonella and other bacterial isolates. Conclusion: In this study, qPCR using the inv A primer set was found to be highly specific for Salmonella detection. All the bloodstream bacterial pathogens in this study were MDR; thus, there is a need for continuous evaluation of antibiotics in medical settings. Further molecular studies on these bacterial isolates is essential.","PeriodicalId":34545,"journal":{"name":"Infection Epidemiology and Microbiology","volume":"14 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prevalence of Salmonella Bloodstream Infection and Antimicrobial Resistance in Lagos, Nigeria.\",\"authors\":\"F. Akinkunmi, S. Ajoseh, C. Fakorede, R. Abegunrin, W. Salami, Aminat K. Lawal, K. Akinyemi\",\"doi\":\"10.52547/iem.9.1.1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"(n=6, 10.91%), Proteus species (n=13, 23.64%), Serratia species (n=7, 12.73%), and Citrobacter species (n=2, 3.64%). In this study, the detection rate of Salmonella isolates in positive blood culture samples using qPCR and inv A gene primer set was 100%. Salmonella isolates were %100 resistant to ceftazidime, cefotaxime, and doripenem. Multidrug resistance (MDR) was observed in Salmonella and other bacterial isolates. Conclusion: In this study, qPCR using the inv A primer set was found to be highly specific for Salmonella detection. All the bloodstream bacterial pathogens in this study were MDR; thus, there is a need for continuous evaluation of antibiotics in medical settings. Further molecular studies on these bacterial isolates is essential.\",\"PeriodicalId\":34545,\"journal\":{\"name\":\"Infection Epidemiology and Microbiology\",\"volume\":\"14 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Infection Epidemiology and Microbiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52547/iem.9.1.1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infection Epidemiology and Microbiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52547/iem.9.1.1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Prevalence of Salmonella Bloodstream Infection and Antimicrobial Resistance in Lagos, Nigeria.
(n=6, 10.91%), Proteus species (n=13, 23.64%), Serratia species (n=7, 12.73%), and Citrobacter species (n=2, 3.64%). In this study, the detection rate of Salmonella isolates in positive blood culture samples using qPCR and inv A gene primer set was 100%. Salmonella isolates were %100 resistant to ceftazidime, cefotaxime, and doripenem. Multidrug resistance (MDR) was observed in Salmonella and other bacterial isolates. Conclusion: In this study, qPCR using the inv A primer set was found to be highly specific for Salmonella detection. All the bloodstream bacterial pathogens in this study were MDR; thus, there is a need for continuous evaluation of antibiotics in medical settings. Further molecular studies on these bacterial isolates is essential.