取代内酰胺开环的研究:消除与重排

R. N. Yadav, S. N. Newaz, A. Bose, B. Banik
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引用次数: 0

摘要

内酰胺及其通过重排反应得到的产物是非常有用的化合物,具有多种用途。在对乙烯基内酰胺和内酰胺重排的研究过程中,发现在亲核条件下暴露取代的溴内酰胺醇时,消除反应比重排反应快得多。
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Studies on Substituted Beta Lactams Towards Ring Opening: Elimination Versus Rearrangement
Beta lactams and products obtained from them through rearrangement reactions are extremely useful compounds of diverse interests. During the course of study of vinyl beta lactams and rearrangement of beta lactams, it has been observed that elimination reaction becomes much faster than rearrangement when substituted bromo beta lactam alcohol is exposed under nucleophilic reaction conditions.
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