噪声应激诱导的Wistar白化大鼠行为改变的效果

Dapkupar Wankhar, Rathinasamy Sheela Devi, Iyyasamy Ashok
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引用次数: 16

摘要

据报道,暴露于任何超过90分贝的噪音都是一种压力源。本研究旨在研究补充333 mg/kg/b.wt的黑刺草是否能避免噪音应激引起的Wistar白化大鼠行为改变。噪声应激动物暴露于100 dB(4小时/天),持续15天。与对照组和officinalis处理的动物相比,噪声应激动物在空地试验中固定、饲养、粪便量增加,行走和梳洗明显减少,而在升高+迷宫中,张开臂进入次数和百分比、张开臂时间和百分比明显减少。噪声应激动物经马齿苋处理后,上述各项指标均有所改善,并从应激状态中恢复。结果表明,马齿苋具有抗应激性,其作用机制可能与马齿苋的抗氧化特性有关。
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Emblica officinalis outcome on noise stress induced behavioural changes in Wistar albino rats

Exposure to any kind of noise exceeding 90 dB is reported to be a stressor. This study focuses on whether Emblica officinalis supplement (333 mg/kg/b.wt) could avert the noise stress induced behavioural changes in Wistar albino rats. Noise stress animals were exposed to 100 dB (4 hr/day) for 15 days. When compared to control and E. officinalis treated animals, noise stress animals showed an increased immobilization, rearing, fecal bolus and marked decrease in ambulation and grooming in open field test, whereas in elevated plus maze, it showed a marked decrease in the number of open arm entry and percentage, time spent in open arm and percentage. Noise stress animals treated with E. officinalis showed improvement in all the above observations and recovered from the stress. The results imply that E. officinalis possesses anti-stressor property by reducing the noise stress induced alterations in behaviour, its effect might be due to the antioxidant property of E. officinalis.

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