超声引导下冠状与轴状视神经鞘直径测量在颅内压增高患者中的比较研究

Noha Osama AlMobaiad, R. M. Mohamed, Mohamed Ibrahem Okab, A. Hamed, Mohamed Lotfy
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摘要

背景:本研究旨在比较超声引导下冠状和轴状视神经鞘直径(ONSD)测量在颅内压升高(ICP)危险患者中的有效性和精度。视神经是长约5cm的管状结构,其眶内节段可在超声检查中发现。方法:在这项前瞻性、随机、双盲试验中,70例患者年龄从18岁到60岁,在转入重症监护病房(ICU)时患有中度至重度创伤性脑损伤(TBI), GCS为3-12。有两组患者:A组患者在脑CT扫描中没有表现出升高的ICP读数。B组:颅脑CT扫描发现颅内压升高的患者。结果:两组患者冠状面平均ONSD均高于轴向平均ONSD,差异无统计学意义。B组患者的平均ONSD、平均轴状和冠状ONSD显著升高。此外,两类患者的平均ONSD、平均冠状和轴状ONSD (mm)与GCS之间存在显著的负相关。结论:在颅脑外伤患者中,床边眼超声监测视神经鞘直径是早期发现颅内压过高的一种有益的无创方法,通过轴位和冠状两种方法的相关性可以获得更准确的测量结果。
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Comparative study between ultrasound guided coronal versus axial optic nerve sheath diameter measurement in patients at risk of increased intracranial pressure
Background: This work intended to contrast the effectiveness as well as precision of ultrasound guided coronal versus axial optic nerve sheath diameter (ONSD) measurement in patients at danger of elevated intracranial pressure (ICP). The optic nerve is a tubular structure of approximately 5 cm in Length, in which its intraorbital segment is evaluable sonographically. Methods: The 70 patients in this prospective, randomised, double-blinded trial spanned in age from 18 to 60 and had moderately to grave traumatic brain injury (TBI) when they were transferred to the intensive care unit (ICU) with a GCS of 3-12. There were two groups of patients: Patients in Group A do not exhibit elevated ICP readings on brain CT scans. Group B: Patients who had elevated ICP found on a brain CT scan. Results: There were non-significant higher mean coronal ONSD in comparison to mean axial ONSD in both groups. significant higher mean ONSD and mean axial and coronal ONSD in patients of group B. The Glasgow Coma Scale (GCS) was considerably lower in group B patients. In addition, there was a substantial inverse correlation between the mean ONSD, mean coronal and axial ONSD (mm), and the GCS for patients in both categories. Conclusions: In patients with trauma to the brain, monitoring the diameter of the optic nerve sheath with bedside ocular ultrasonography is a beneficial non-invasive way to detect excessive intracranial pressure earlier and correlation via the two methods (axial and coronal) gives us more accurate measurements.
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