塞尔维亚银屑病患者银屑病关节炎患病率的前瞻性队列研究

E. Mahmutovic, Emir Bisevac, Ardea Milidrag, Z. Bajin, K. Boskovic, Z. Dolicanin
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摘要

目的:本研究的目的是确定银屑病关节病的发病率和患病率,并指出其在诊断为银屑病的患者样本中发生的问题。方法:对109例诊断为银屑病及银屑病关节病的患者进行调查。患者平均年龄48、85±10、11岁。分析银屑病患者银屑病性关节病的发病率和患病率。结果:银屑病关节病患者以骶髂关节关节炎改变为主,其中男性19例(79.17%),女性5例(20.83%)(p< 0.001);脊柱11例(10.09%),男性6例(54.56%),女性5例(45.45%)(p= 0.578);外周关节74例(67.89%),男性33例(44.59%),女性41例(55.41%)(p< 0.01)。比较症状时,大多数患者(63,30%)皮肤变化出现在关节炎之前,27,52%的患者皮肤变化发生在关节炎之前,9,17%的患者皮肤变化同时发生。结论:银屑病关节病多见于中位年龄(31 ~ 50岁),男性多于女性。大多数银屑病患者的皮肤变化先于关节病变,最常见的是多发性关节炎。
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A Prospective Cohort Study of Psoriatic Arthritis Prevalence in a Serbian Patients with Psoriasis
Objective: The aim of this study was to determine the incidence and prevalence of psoriatic arthropathy and to point out the problem of their occurrence in a sample of patients diagnosed with psoriasis. Methods: 109 patients with diagnosed psoriasis and psoriatic arthropathy, took part in the survey. The average age of patients was 48,85±10,11. We analyzed the incidence and prevalence of the psoriatic arthropathy occurrence for the patients with psoriasis. Results: Psoriatic arthropathy registered with patients were those with arthritic changes on: sacroiliac joints with 24 (22,02%) patients, 19 (79,17%) male and 5 (20,83%) female (p<0,001); spine with 11 (10,09%) patients, 6 (54,56%) male and 5 (45,45%) female (p=0,578); peripheral joints with 74 (67,89%) patients, 33 (44,59%) male and 41 (55,41%) female (p<0,01). When comparing the symptoms, most of the patients (63,30%) skin changes were represented before arthritis, for 27,52% patients arthritis preceded the skin changes, and for 9,17% patients the changes were simultaneous, Conclusion: Psoriatic arthropathy occurs more often in median age (31 to 50 years old) and it is more common for men than women. For most patient’s psoriatic skin changes preceded joints affection, with the most common ones being polyarthritis.
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