T. Hsiai, S. Cho, P. Wong, M. Ing, M. Navab, S. Reddy, L. Demer, C. Ho
{"title":"生物mems传感器实时剪切应力内皮细胞动力学","authors":"T. Hsiai, S. Cho, P. Wong, M. Ing, M. Navab, S. Reddy, L. Demer, C. Ho","doi":"10.1109/IEMBS.2002.1053047","DOIUrl":null,"url":null,"abstract":"Precise characterization of shear stress in the arterial trees is critical to elucidate the effects of spatial versus temporal shear stress gradients on the biological activities of endothelial cells (EC). We developed micro electrical mechanical systems (MEMS) sensors, comparable to the size of EC (2 /spl times/ 80 /spl mu/m), to deliver the spatial and temporal resolution necessary at a frequency response > 100 Hz. We provided the first in vitro evidence of real-time wall shear stress on EC couple with real-time gene expression of monocyte chemoattractant protein (MCP-1).","PeriodicalId":60385,"journal":{"name":"中国地球物理学会年刊","volume":"4 1","pages":"1828-1829 vol.3"},"PeriodicalIF":0.0000,"publicationDate":"2002-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"10","resultStr":"{\"title\":\"Bio-MEMS sensors for real-time shear stress on endothelial cell dynamics\",\"authors\":\"T. Hsiai, S. Cho, P. Wong, M. Ing, M. Navab, S. Reddy, L. Demer, C. Ho\",\"doi\":\"10.1109/IEMBS.2002.1053047\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Precise characterization of shear stress in the arterial trees is critical to elucidate the effects of spatial versus temporal shear stress gradients on the biological activities of endothelial cells (EC). We developed micro electrical mechanical systems (MEMS) sensors, comparable to the size of EC (2 /spl times/ 80 /spl mu/m), to deliver the spatial and temporal resolution necessary at a frequency response > 100 Hz. We provided the first in vitro evidence of real-time wall shear stress on EC couple with real-time gene expression of monocyte chemoattractant protein (MCP-1).\",\"PeriodicalId\":60385,\"journal\":{\"name\":\"中国地球物理学会年刊\",\"volume\":\"4 1\",\"pages\":\"1828-1829 vol.3\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2002-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"10\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中国地球物理学会年刊\",\"FirstCategoryId\":\"1089\",\"ListUrlMain\":\"https://doi.org/10.1109/IEMBS.2002.1053047\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国地球物理学会年刊","FirstCategoryId":"1089","ListUrlMain":"https://doi.org/10.1109/IEMBS.2002.1053047","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Bio-MEMS sensors for real-time shear stress on endothelial cell dynamics
Precise characterization of shear stress in the arterial trees is critical to elucidate the effects of spatial versus temporal shear stress gradients on the biological activities of endothelial cells (EC). We developed micro electrical mechanical systems (MEMS) sensors, comparable to the size of EC (2 /spl times/ 80 /spl mu/m), to deliver the spatial and temporal resolution necessary at a frequency response > 100 Hz. We provided the first in vitro evidence of real-time wall shear stress on EC couple with real-time gene expression of monocyte chemoattractant protein (MCP-1).
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
