Analysis of rationality of pharmacotherapy with oral anticoagulants in a trauma hospital

The article presents the results of the study of safety of oral anticoagulants (OACs) use in trauma patients.Venous thromboembolic complications (VTEC) after surgery are among the most common indications for prescribing direct oral anticoagulants (OACs) in elderly patients, the treatment of which can cause serious problems and is associated with age-related characteristics of the organism. The purpose — to study the safety of using oral anticoagulants (OACs) use in a trauma hospital. Material and methods. A retrospective analysis was performed of 120 medical records of inpatients receiving oral anticoagulants to prevent blood clots after reconstructive surgery for bone fractures.In the study, 2 groups were considered: group 1 (without violations of hemostasis) — 50 people, aged 54.6 ± 18.0, group 2 (with impaired hemostasis) — 70 people, aged 61.3 ± 21.5. Conclusions. There is a cause-and-effect relationship between a violation of hemostasis indicators (mainly an increase in APTT) and risk factors.