Pharmacological, Phytochemistry and Ethnomedicinal profiles of Osyris quadripartita Salz. Ex Decne.: A Critical Review

Osyris quadripartita Salz. ex Decne. (Santalaceae), prominently known as African sandalwood, is one of the most seasoned and most valuable sources of natural fragrance with immense medicinal and commercial significance. O quadripartita has been grown in Africa and Indian sub- continents from the ancient times and esteemed all over the world for its tonic, and the aromatic oils are used in different products for manufacturing expensive perfumes, rare soaps, quality lotions, and sweet-smelling candles. Leaf stem bark and African shoe heart wood the essential oil derived from African sandalwood has been used in various traditional and tribal systems of medicine, like Ayurveda, Siddha, Folk and Unani medicine, in the treatment and counteraction of a great many sicknesses. It is utilized to treat different illnesses, including helminth contaminations, leishmaniases like infection, irregularities, kidney sickness, scavenge, sterile/perfuming, eye torment, cool, anaphylactic shock, epilepsy, circumcision wounds, toothache, tonsillitis, stomach agony, and pee issues. The flexible restorative and medical services significance of sandalwood is ascribed to its rich essential oil of phytochemicals, especially sesquiterpenes. African sandalwood, recently utilized for its ancestral modern purposes, is presently acquiring consideration for its helpful as well as food and nutraceutical utilizes. An intensive bibliographic examination was done by dissecting overall acknowledged logical data sets such as Google scholar, Publons, Sci-Finder, Pub Med, Scopus, Web of Science, Research Gate, perceived reference books, and UGC Care listed as well as non-listed international journals. Current pharmacological examinations have shown a great many pharmacological activities, going from antimicrobial to anti-cancer. No huge poisonousness has been demonstrated by African sandalwood essential oil and its singular constituents; in any case, further concentrate on compound constituents and their components in showing specific natural exercises is expected to comprehend the full phytochemical profile and the complex pharmacological impacts of this plant. The expanded business abuse of African sandalwood and low efficiency of this huge restorative plant have raised worries over its preservation and efficiency upgrade through current instruments and procedures. The complete survey examines conventional purposes, ancestral purposes, ethnopharmacology, phytochemistry, and biological activities of African sandalwood to unveil its restorative and modern worth and distinguish holes requiring future exploration.