呼吸康复在矫正小气道功能障碍中的可能性

N. S. Yubitskaya, M. Antonyuk, T. Gvozdenko
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摘要

介绍。现在已经认识到小气道功能障碍是慢性阻塞性疾病发展的一个组成部分。小气道损害是支气管哮喘和慢性阻塞性肺疾病某些表型的特征,这决定了疾病的临床表现特点,需要个性化的治疗方法。从慢性阻塞性疾病对小气道的影响方面,综述了国内外研究人员对慢性阻塞性疾病采用非药物康复方法的可能性的资料。材料和方法。该综述使用的数据来自PubMed、Google Scholar、eLIBRARY.Results等网站上发表的文章。本文介绍了评估小气道的现代方法。讨论了康复治疗阶段小气道功能障碍诊断标准的选择和复杂性。使用自然和预先形成的物理因素在慢性阻塞性肺疾病的康复治疗中的有效性已被证明。作者分析了物理治疗因素对肺活量测定参数动态的影响,间接指示小气道的状态。具有穿透远端呼吸道的超小尺寸药物颗粒的吸入制剂的优选显示。重点讨论了自然因素和人工因素对慢性阻塞性肺疾病小气道功能障碍的影响。文献资料表明,肺康复方法对小气道功能障碍有积极作用。物理治疗因子在呼吸道外周部位的作用机制及针对性医疗技术的发展有待进一步研究。
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Possibilities of respiratory rehabilitation in correction of small airway dysfunction
Introduction. It is now recognized that small airway dysfunction is a component of the development of chronic obstructive diseases. The damage of the small airways is characteristic of certain phenotypes of bronchial asthma and chronic obstructive pulmonary disease, which determines the characteristics of the clinical manifestations of the disease and requires a personalized approach to treatment.Aim. Summarizing the data of domestic and foreign researchers on the possibility of using non-drug methods of rehabilitation of chronic obstructive diseases in terms of their impact on the small airways.Materials and methods. The review uses data from articles published in PubMed, Google Scholar, eLIBRARY.Results. The article presents modern methods for assessing small airways. The choice of criteria and the complexity of diagnosing small airway dysfunction at the stage of rehabilitation treatment are discussed. The effectiveness of the use of natural and preformed physical factors in the rehabilitation treatment of chronic obstructive pulmonary diseases has been shown. The authors analyze the influence of physiotherapeutic factors on the dynamics of spirometry parameters, indirectly indicating the state of small airways. The preferred choice of inhalation preparations with extrasmall sizes of medicinal particles penetrating into the distal respiratory tract is shown. The influence of natural and preformed physical factors on the small airway dysfunction in chronic obstructive pulmonary diseases is highlighted.Conclusion. Literature data suggest a positive effect of pulmonary rehabilitation methods on the small airway dysfunction. Further studies are required to study the mechanisms of action of physiotherapeutic factors on the peripheral parts of the respiratory tract and the development of targeted medical technologies.
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