{"title":"热均质法制备对乙酰氨基酚固体脂质纳米颗粒及评价","authors":"Ayesha Siddiqua Gazi, A. Krishnasailaja","doi":"10.15406/jnmr.2018.07.00184","DOIUrl":null,"url":null,"abstract":"The solid lipid nanoparticles (SLNs) are sub-micron colloidal carriers (50-100nm) which are composed of physiological lipid dispersed in water or in an aqueous surfactant solution.1 SLNs are colloidal drug carrier combines the advantages of polymeric nanoparticles, fat emulsion and liposomes simultaneously and avoiding some of their disadvantages.2 To overcome the disadvantages associated with the liquid state of the oil droplets, the liquid lipid was replaced by a solid lipid which eventually transformed into solid lipid nanoparticles.3","PeriodicalId":16465,"journal":{"name":"Journal of Nanomedicine Research","volume":"31 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":"{\"title\":\"Preparation & evaluation of paracetamol solid lipid nanoparticles by hot homogenization method\",\"authors\":\"Ayesha Siddiqua Gazi, A. Krishnasailaja\",\"doi\":\"10.15406/jnmr.2018.07.00184\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The solid lipid nanoparticles (SLNs) are sub-micron colloidal carriers (50-100nm) which are composed of physiological lipid dispersed in water or in an aqueous surfactant solution.1 SLNs are colloidal drug carrier combines the advantages of polymeric nanoparticles, fat emulsion and liposomes simultaneously and avoiding some of their disadvantages.2 To overcome the disadvantages associated with the liquid state of the oil droplets, the liquid lipid was replaced by a solid lipid which eventually transformed into solid lipid nanoparticles.3\",\"PeriodicalId\":16465,\"journal\":{\"name\":\"Journal of Nanomedicine Research\",\"volume\":\"31 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-04-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Nanomedicine Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15406/jnmr.2018.07.00184\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Nanomedicine Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15406/jnmr.2018.07.00184","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Preparation & evaluation of paracetamol solid lipid nanoparticles by hot homogenization method
The solid lipid nanoparticles (SLNs) are sub-micron colloidal carriers (50-100nm) which are composed of physiological lipid dispersed in water or in an aqueous surfactant solution.1 SLNs are colloidal drug carrier combines the advantages of polymeric nanoparticles, fat emulsion and liposomes simultaneously and avoiding some of their disadvantages.2 To overcome the disadvantages associated with the liquid state of the oil droplets, the liquid lipid was replaced by a solid lipid which eventually transformed into solid lipid nanoparticles.3
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