由锇酸引起的滑液变化。

G. Lörincz, H. Isomäki, J. Martio
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引用次数: 0

摘要

摘要对27例风湿性膝关节积液患者进行了锇酸对滑膜液的影响研究。特别关注的是滑膜白细胞计数和电泳模式。在滑膜样本中,白细胞减少先于白细胞增多;两者都被认为是由锇引起的。透明质酸形成的沉淀被认为是白细胞减少的原因,这提出了一个关于锇酸作用的新假设。在电泳图谱中,蛋白质的电荷发生了变化。注射锇酸一周后,形态正常。
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Changes in the synovial fluid caused by osmic acid.
Summary27 rheumatic patients with knee joint hydrops were studied for the effect of osmic acid on the synovial fluid. Special interest was taken in synovial leucocyte counts and electrophoretic patterns. A leucopenia preceded the leucocytosis in the synovial samples; both were thought to be induced by osmium. A precipitate formation from hyaluronate was thought to account for the leucopenia and this suggests a new hypothesis of osmic acid action. In the electrophoretic patterns there was a change in the electric charges of proteins. One week after osmic acid injection the pattern was normal.
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