法匹拉韦治疗Covid-19的回顾性分析

S. Kulzhanova, M. Konkayeva, Z. Smagulova, Nazira N. Beisenbieva, G. Tuleshova, A. Utegenova, G. O. Turebaeva, Gaukhar A. Nurakhmetova
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引用次数: 2

摘要

法匹拉韦(FPV)是治疗COVID-19的潜在药物之一。本回顾性研究比较了(FVP组)和(对照组)使用法匹拉韦治疗COVID-19。两组患者的人口学特征和初始临床指标具有可比性。与对照组相比,FVP组血氧饱和度、呼吸频率和胸痛发生率恢复正常的时间明显早于对照组(第7天)(p<0.05)。FVP组患者病情改善明显早于对照组(p <0.001)。综上所述,FVP治疗的疗效高于对照管理策略,并建立了一套个性化的治疗剂。然而,需要更详细的研究来充分评估favipiravir治疗COVID-19的疗效。
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A Retrospective Analysis of Treatment of Covid-19 with Favipiravir
Summary One of the potential therapeutic agents for treating COVID-19 is favipiravir (FPV). This retrospective study compared the treatment of COVID-19 with (FVP group) or without (control group) favipiravir. Demographic characteristics and initial clinical indicators in the two groups were comparable. The level of oxygen saturation, respiratory rate, and prevalence of chest pain in the FVP group returned to normal significantly earlier (on the seventh day) compared to the control group (p<0.05). Improvement of patients’ condition in the FVP group occurred significantly earlier than in the control group (p <0.001). In conclusion, FVP treatment’s efficacy was higher than the control management strategy and established an individualized set of therapeutic agents. However, more detailed studies are needed to evaluate the efficacy of COVID-19 treatment with favipiravir fully.
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