{"title":"弓形虫病和交叉反应:免疫印迹分析血清学反应","authors":"J. Dave, D.S. Tompkins, R.P. Eglin, J.P. Harford","doi":"10.1016/S0888-0786(96)80009-6","DOIUrl":null,"url":null,"abstract":"<div><p>Antibodies which react with toxoplasma antigens (natural antibodies) can be found in patients without other evidence of toxoplasma infection. The natural antibody profile of 37 sera which were Dye Test (DT) negative was investigated by Western blotting with toxoplasma antigens. These 37 sera comprised 11 which were indirect haemagglutination test positive for toxoplasma antibodies, 8 rheumatoid factor positive and 18 from patients with acute viral infections. These three groups of sera could not be distinguished from each other, or from pooled sera from patients not infected with toxoplasma, by characterising the Western blot reactions.</p></div>","PeriodicalId":101161,"journal":{"name":"Serodiagnosis and Immunotherapy in Infectious Disease","volume":"8 2","pages":"Pages 109-116"},"PeriodicalIF":0.0000,"publicationDate":"1996-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0888-0786(96)80009-6","citationCount":"1","resultStr":"{\"title\":\"Toxoplasmosis and cross-reactivity: an analysis of the serological response by immunoblotting\",\"authors\":\"J. Dave, D.S. Tompkins, R.P. Eglin, J.P. Harford\",\"doi\":\"10.1016/S0888-0786(96)80009-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Antibodies which react with toxoplasma antigens (natural antibodies) can be found in patients without other evidence of toxoplasma infection. The natural antibody profile of 37 sera which were Dye Test (DT) negative was investigated by Western blotting with toxoplasma antigens. These 37 sera comprised 11 which were indirect haemagglutination test positive for toxoplasma antibodies, 8 rheumatoid factor positive and 18 from patients with acute viral infections. These three groups of sera could not be distinguished from each other, or from pooled sera from patients not infected with toxoplasma, by characterising the Western blot reactions.</p></div>\",\"PeriodicalId\":101161,\"journal\":{\"name\":\"Serodiagnosis and Immunotherapy in Infectious Disease\",\"volume\":\"8 2\",\"pages\":\"Pages 109-116\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1996-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0888-0786(96)80009-6\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Serodiagnosis and Immunotherapy in Infectious Disease\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0888078696800096\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Serodiagnosis and Immunotherapy in Infectious Disease","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0888078696800096","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Toxoplasmosis and cross-reactivity: an analysis of the serological response by immunoblotting
Antibodies which react with toxoplasma antigens (natural antibodies) can be found in patients without other evidence of toxoplasma infection. The natural antibody profile of 37 sera which were Dye Test (DT) negative was investigated by Western blotting with toxoplasma antigens. These 37 sera comprised 11 which were indirect haemagglutination test positive for toxoplasma antibodies, 8 rheumatoid factor positive and 18 from patients with acute viral infections. These three groups of sera could not be distinguished from each other, or from pooled sera from patients not infected with toxoplasma, by characterising the Western blot reactions.
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