维生素D不足/缺乏的患病率及其在儿童特应性皮炎发展和病程中的作用

Tatiana S. Kashinskaya, N. Shakhova, Yrij F. Lobanov, E. M. Kamaltynova
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引用次数: 0

摘要

近几十年来,关于维生素D在特应性皮炎(AD)发病机制中的作用的各种确凿证据已经获得。许多研究表明,AD患者血液中25(OH)D浓度低,并伴有高浓度的过敏原特异性IgE(据多篇报道)。本文分析了低25(OH)D浓度的患病率,维生素D缺乏与AD严重程度和对过敏原的敏感性的关系,以及维生素D紊乱与AD发展风险的关系。
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Prevalence of Vitamin D Insufficiency/Deficiency and Their Role in Atopic Dermatitis Development and Course in Children
Various conclusive evidence on the role of vitamin D in the pathogenesis of atopic dermatitis (AD) has been obtained in recent decades. Many studies have shown that patients with AD have low concentration of 25(OH)D in blood associated with high concentration of allergen specific IgE (according to several reports). The analysis of low 25(OH)D concentration prevalence, association of vitamin D deficiency with AD severity and sensitization to allergens, and association of vitamin D disorders with risk of AD development is presented.
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