Etiological study of blood stream infection in a maternal and child healthcare based tertiary hospital

Bloodstream infections by bacterial pathogens are major cause of morbidity and mortality in developing countries. The aim of this study was to identify the bacterial pathogens causing bloodstream infections in certain areas of Dhaka, Bangladesh and determine their antibiotic susceptibility pattern according to age group.: A total of 6095 blood samples were collected from patients attending at Ad-din Women’s Medical College & Hospital from July 2019 to December 2020. All the blood samples were processed for culture using a BACT/Alert blood culture machine. Further identification & antimicrobial susceptibility tests were performed using standard microbiological procedures. Overall, 10.6% of the cultured blood samples were growth positive. Out of them, Gram-negative bacilli were predominant. Blood stream infection rate is highest among neonates, followed by the age group of 1-15 years, adult patients, with minimum rate observed among the age group of 1 month- 1 Year. was the most frequently isolated among the Growth positive samples, followed by Coagulase negative (CONS), , , species. The most frequently isolated pathogens among Neonates were Coagulase negative Spp, and Spp; whereas was most commonly isolated pathogen among pediatrics and adult age group (p=<.001). However, we observe a decreasing trend in the isolation & the percentage of multi drug resistance amongst spp. in the study period than studies conducted over previous years. A remarkable increase of susceptibility against chloramphenicol & cotrimoxazole has been observed in this study. However, Gram positive organisms show high sensitivity to imepenem, vancomycin and linezolid. This study identified the bacterial pathogens involved with BSI in our hospital among different age groups and their antibiotic susceptibility patterns, so that, healthcare professionals can make proper decisions and provide better care for their patients.