{"title":"胃肠道间质瘤","authors":"X. Bi","doi":"10.1159/isbn.978-3-318-06329-5","DOIUrl":null,"url":null,"abstract":"Gastrointestinal stromal tumors(GIST) is a kind of tumor which originated from gastrointestinal submucosa,of which the molecular biological mechanism is the mutation of proto-oncogene c-kit.Its clinical characteristics is that it can occur in the whole gastrointestinal tract,especily in stomach as well as lack of specific clinical manifestation.Imaging examination has high value in judging morphology questions including its biological behavior,structural feature and so on.Its immunohistochemistry almost shows positive CD34、CD117.Its diagnosis depends on combined application of clinical manifestation,imaging changes,pathological morphology and immunohistochemistry.Surgery is the main therapeutic method although there are great breakthrough in its molecular targeted therapy.","PeriodicalId":18478,"journal":{"name":"医学综述","volume":"128 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Gastrointestinal Stromal Tumors\",\"authors\":\"X. Bi\",\"doi\":\"10.1159/isbn.978-3-318-06329-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Gastrointestinal stromal tumors(GIST) is a kind of tumor which originated from gastrointestinal submucosa,of which the molecular biological mechanism is the mutation of proto-oncogene c-kit.Its clinical characteristics is that it can occur in the whole gastrointestinal tract,especily in stomach as well as lack of specific clinical manifestation.Imaging examination has high value in judging morphology questions including its biological behavior,structural feature and so on.Its immunohistochemistry almost shows positive CD34、CD117.Its diagnosis depends on combined application of clinical manifestation,imaging changes,pathological morphology and immunohistochemistry.Surgery is the main therapeutic method although there are great breakthrough in its molecular targeted therapy.\",\"PeriodicalId\":18478,\"journal\":{\"name\":\"医学综述\",\"volume\":\"128 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-11-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"医学综述\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1159/isbn.978-3-318-06329-5\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"医学综述","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1159/isbn.978-3-318-06329-5","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Gastrointestinal stromal tumors(GIST) is a kind of tumor which originated from gastrointestinal submucosa,of which the molecular biological mechanism is the mutation of proto-oncogene c-kit.Its clinical characteristics is that it can occur in the whole gastrointestinal tract,especily in stomach as well as lack of specific clinical manifestation.Imaging examination has high value in judging morphology questions including its biological behavior,structural feature and so on.Its immunohistochemistry almost shows positive CD34、CD117.Its diagnosis depends on combined application of clinical manifestation,imaging changes,pathological morphology and immunohistochemistry.Surgery is the main therapeutic method although there are great breakthrough in its molecular targeted therapy.
期刊介绍：
Medical Recapitulate is a bimonthly magazine and is a national comprehensive medical professional journal supervised by the National Health Commission of the People's Republic of China and sponsored by the Chinese Medical Doctor Association. Founded in 1994, the magazine has gone through changes from a monthly magazine with 48 pages to 96 pages, and then from a monthly magazine to a bimonthly magazine with 208 pages. The main columns of this journal: Review · Molecular biomedicine, oncology, clinical medicine, clinical pharmacy, laboratory medicine, anesthesiology, medical imaging, endoscopy, traditional Chinese medicine, integrated traditional Chinese and Western medicine, syndromes, diabetes, etc., monographs, Clinical research articles.
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