Letian Zhang , Kai Zheng , Pengfei Zhang , Min Jiang , Jiabin Shen , Chao Chen , Chao Shen
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Visible-light-enabled multicomponent synthesis of trifluoromethylated 3-indolequinoxalin-2(1H)-ones without external photocatalysis
A novel and sustainable visible-light-enabled multicomponent reaction involving quinoxalin-2(1H)-ones, indoles, and CF3SO2Na that does not require an external photocatalyst is described. This photoinduced reaction employs air as the sole oxidant, thereby providing a green and highly step-efficient approach to a series of biologically important trifluoromethylated 3-indolequinoxalin-2(1H)-ones.