{"title":"纳米粒子在眼科医学中的应用","authors":"Y. Qazi, Brian C. Stagg, B. Ambati","doi":"10.1080/14634980902908514","DOIUrl":null,"url":null,"abstract":"ABSTRACT Over the past decade, nanoparticles have risen to the forefront of biotechnology, promising diverse applications in the fields of gene therapy, drug delivery, and imaging. Nanoparticles can be engineered to create optimal features that are tissue-specific or target-orientated to promote their uptake, clearance, biodegradability, reduced immunogenicity, and detection. Nanomedicine offers potentially safe and successful treatment regimens for ocular disorders. In this review, the authors focus on the ophthalmic applications of nanoparticles, with particular attention to gene therapy and drug delivery.","PeriodicalId":88525,"journal":{"name":"International journal of green nanotechnology. Biomedicine","volume":"128 1","pages":"3-8"},"PeriodicalIF":0.0000,"publicationDate":"2009-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Nanoparticles in Ophthalmic Medicine\",\"authors\":\"Y. Qazi, Brian C. Stagg, B. Ambati\",\"doi\":\"10.1080/14634980902908514\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"ABSTRACT Over the past decade, nanoparticles have risen to the forefront of biotechnology, promising diverse applications in the fields of gene therapy, drug delivery, and imaging. Nanoparticles can be engineered to create optimal features that are tissue-specific or target-orientated to promote their uptake, clearance, biodegradability, reduced immunogenicity, and detection. Nanomedicine offers potentially safe and successful treatment regimens for ocular disorders. In this review, the authors focus on the ophthalmic applications of nanoparticles, with particular attention to gene therapy and drug delivery.\",\"PeriodicalId\":88525,\"journal\":{\"name\":\"International journal of green nanotechnology. Biomedicine\",\"volume\":\"128 1\",\"pages\":\"3-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2009-08-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International journal of green nanotechnology. Biomedicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/14634980902908514\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of green nanotechnology. Biomedicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/14634980902908514","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
ABSTRACT Over the past decade, nanoparticles have risen to the forefront of biotechnology, promising diverse applications in the fields of gene therapy, drug delivery, and imaging. Nanoparticles can be engineered to create optimal features that are tissue-specific or target-orientated to promote their uptake, clearance, biodegradability, reduced immunogenicity, and detection. Nanomedicine offers potentially safe and successful treatment regimens for ocular disorders. In this review, the authors focus on the ophthalmic applications of nanoparticles, with particular attention to gene therapy and drug delivery.