纳米粒子在眼科医学中的应用

Y. Qazi, Brian C. Stagg, B. Ambati
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引用次数: 4

摘要

在过去的十年中,纳米颗粒已经上升到生物技术的前沿,在基因治疗、药物传递和成像等领域有着广泛的应用前景。纳米颗粒可以被设计成具有组织特异性或靶向性的最佳特征,以促进它们的吸收、清除、生物降解性、降低免疫原性和检测。纳米医学为眼部疾病提供了潜在的安全和成功的治疗方案。本文综述了纳米颗粒在眼科的应用,特别是在基因治疗和药物传递方面的应用。
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Nanoparticles in Ophthalmic Medicine
ABSTRACT Over the past decade, nanoparticles have risen to the forefront of biotechnology, promising diverse applications in the fields of gene therapy, drug delivery, and imaging. Nanoparticles can be engineered to create optimal features that are tissue-specific or target-orientated to promote their uptake, clearance, biodegradability, reduced immunogenicity, and detection. Nanomedicine offers potentially safe and successful treatment regimens for ocular disorders. In this review, the authors focus on the ophthalmic applications of nanoparticles, with particular attention to gene therapy and drug delivery.
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