变异病毒大流行与社会:多尺度活性粒子方法

N. Bellomo, D. Burini, N. Outada
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引用次数: 12

摘要

本文在多尺度框架内介绍了对COVID-19大流行建模的统一方法的探索,从传染到宿主内部动态。该模型的重点是疫苗接种和一般治疗行动。我们文章的第一部分致力于理解系统的复杂特征和建模原理的设计。然后,接下来的建模方法主要集中在增殖病毒和免疫系统之间的竞争。建模还考虑了与新变种发生有关的疫苗接种计划的行动。本文是“社会和经济的动态交换模型”主题的一部分。
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Pandemics of mutating virus and society: a multi-scale active particles approach
This article presents, within a multiscale framework, a search for a unified approach towards modelling the COVID-19 pandemic, from contagion to within-host dynamics. The modelling is focused on vaccination and therapeutical actions in general. The first part of our article is devoted to understanding the complex features of the system and to the design of a modelling rationale. Then, the modelling approach follows mainly focused on the competition between the proliferating virus and the immune system. Modelling considers also the action of vaccination plans related to the onset of new variants. This article is part of the theme issue ‘Kinetic exchange models of societies and economies’.
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