洋葱伯克氏菌:一种罕见的肺炎病因

Arjun A S, Prasanna Kumar T, Manjunath H K
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摘要

洋葱伯克氏菌是一种革兰氏阴性菌,是一种罕见的肺炎病因。当被孤立时,它通常代表殖民。在免疫功能受损的情况下,它可以引起疾病,从轻微的疾病到高度致命的Cepacia综合征。这种有机体对许多抗生素具有内在的耐药性。我们报告一位57岁男性农民,患有糖尿病和支气管哮喘,表现为急性高热、腹痛和咳嗽史。他被诊断为肝脓肿破裂,感染扩散到右下叶。进行剖腹手术。脓液培养培养出铜绿假单胞菌。抗生素治疗后病情有所好转,但一个月后复发,出现严重咳嗽,胸部x光片显示右下肺叶有肺脓肿。支气管肺泡灌洗培养出洋葱伯克霍尔德菌,并开始使用敏感抗生素,但患者还是死于疾病。这种有机物的潜在来源是他经常使用的雾化溶液。当在医院或家庭使用医疗溶液时,重点应放在改进无菌操作的必要性上。怀疑指数可以指导易感个体的最佳抗生素处方实践。
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Burkholderia cepacia: An unusual cause of pneumonia
Burkholderia Cepacia is a gram negative organism, an uncommon cause of pneumonia. When isolated, it usually represents colonisation. In the presence of immunocompromising conditions, it can cause disease, ranging from mild illness to the highly fatal Cepacia syndrome. The organism is intrinsically resistant to many antibiotics. We report a 57 years old male farmer, who has diabetes mellitus and bronchial asthma, who presented with a acute history of high grade fever, pain abdomen and cough. He was diagnosed with a ruptured liver abscess, with the infection spreading to the right lower lobe. Laparotomy was performed. Pus culture grew Pseudomonas aeruginosa. He improved upon antibiotic therapy, only to return after one month with severe cough, chest X-ray revealing a lung abscess in the right lower lobe. Bronchoalveolar lavage culture grew Burkholderia cepacia, and sensitive antibiotics were initiated, however the patient succumbed to the illness. The implicated source of the organism was the nebulisation solution which he was using regularly. Emphasis should be laid on the need for improved aseptic practices while using medical solutions at either hospital or home setting. An index of suspicion may guide optimal antibiotic prescription practices in susceptible individuals.
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