沙达方治疗蛔虫病疗效的开放标记试验研究

R. Savitha
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摘要

肠道蠕虫感染是一种常见的儿童健康问题,引起发病率和痛苦。Sadhakuppai Chooranam是一种传统的Siddha药物,用于治疗儿童常见的蛔虫病。目前的研究是在金奈坦巴拉姆市Siddha国立研究所Kuzhanthai Maruthuvam部门的40名儿科患者(30名门诊患者和10名住院患者)中进行的。试验药物Sadhakuppai Chooranam每天两次,连续20天,每7天随访一次。每次就诊时均进行临床评估并记录预后。试验第0天和第20天分别进行实验室检查,并随访2个月。研究数据进行了仔细的分析,并在本工作中以图形形式呈现。研究结果显示,在40名参加开放标签先导研究的患者中,80%的患者预后非常好,临床和实验室参数均有所改善。因此,试验药物Sadhakuppai Chooranam可用于临床有效治疗蛔虫病(Kudal kirumi)。
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AN OPEN LABELLED PILOT STUDY ON THE EFFICACY OF SIDDHA FORMULATION SADHAKUPPAI CHOORANAM FOR THE TREATMENT OF KUDAL KIRUMI (ASCARIASIS)
Intestinal worm infection is a common pediatric health problem causing morbidity and anguish. Sadhakuppai Chooranam is a traditional Siddha drug indicated for Kudal kirumi (Ascariasis) a common ailment among children. The current study was conducted among 40 pediatric patients (30 Out Patients and 10 In Patients) of the department of Kuzhanthai Maruthuvam at National institute of Siddha, Tambaram, Chennai. The trial drug Sadhakuppai Chooranam was given twice a day for 20 days and follow up was done once in 7 days. At each clinical visit clinical assessment was done and prognosis was noted. Laboratory investigations were done 0 day & 20th day of the trial, and the patients were followed up for another 2 months. The study data were circumspectly analyzed and are presented graphically in this work. The study results revealed that among the forty patients enrolled in the open labeled pilot study, 80% of them had very good prognosis with improvement in both clinical and laboratory parameters. Hence the trial drug Sadhakuppai Chooranam can be used clinically for the effective treatment of Kudal kirumi (Ascariasis).
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