i/k-卡拉胶与聚乙烯醇复合制备辐照水凝胶的特性

B. Utomo, D. Fransiska, La Ode Sumarlin, Ihya Sulthonuddin
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引用次数: 0

摘要

来自热带水域的真麒峰藻主要含有卡拉胶,这是一种具有生产水凝胶潜力的水胶体。本研究旨在确定由i-和k-卡拉胶与聚乙烯醇(PVA)复合制成的水凝胶的特性,该水凝胶可进一步用于伤口敷料。复合i/k-卡拉胶用量分别为1.0%、1.5%、2.0%、2.5%和3.0% w/w, PVA用量为12.5% w/w。复合i/k-卡拉胶的重量比为6:4。用60Co g射线照射水凝胶,照射剂量分别为25和2 kGy.h-1。复合i-和k-卡拉胶的浓度影响水凝胶的凝胶分数、持水量、抗拉强度、伸长率和表面形貌。以复合i/k-卡拉胶的质量分数为3.0% w/w,得到了辐照复合水凝胶的最佳配方。该配方凝胶率为61.67%,持水量为1067.12%,抗拉强度为32.37 × 10-3 MPa,伸长率为251.67%。有趣的是,具有最佳配方的产品具有多孔表面形态和透明度,适用于伤口敷料目的。
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Characteristics of Irradiated Hydrogel Formulated from Composite i/k-carrageenan Combined with Polyvinyl Alcohol
Eucheuma seaweed from tropical waters habitat mainly contains carrageenan, a type of hydrocolloid potential for hydrogel production. This study aims to determine the characteristics of hydrogel formulated from composite i- and k-carrageenan combined with polyvinyl alcohol (PVA) which, could be used further for wound dressing application. The concentrations of composite i/k-carrageenan used were 1.0%, 1.5%, 2.0%, 2.5% and 3.0% w/w, and the PVA concentration was 12.5% w/w. Composite i/k-carrageenan in a proportion of 6:4 by weight. The hydrogel was irradiated using 60Co g-rays with the irradiation dose of 25 and 2 kGy.h-1. The concentration of composite i- and k-carrageenan influenced the gel fraction, water holding capacity, tensile strength, elongation, and surface morphology of the hydrogel. The optimum formula of irradiated composite hydrogel was obtained from 3.0% w/w of composite i/k-carrageenan. The formula had a gel fraction of 61.67%, water holding capacity of  1067.12%, tensile strength of  32.37 x 10-3 MPa, and elongation of  251.67%. Interestingly, the product with the optimum formula had a porous surface morphology and transparency, which are applicable for wound dressing purposes.
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来源期刊
CiteScore
1.40
自引率
0.00%
发文量
10
审稿时长
16 weeks
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