{"title":"新型siRNA与人群健康管理","authors":"L. Walker","doi":"10.1002/psb.2037","DOIUrl":null,"url":null,"abstract":"Inclisiran (Leqvio) is a first‐in‐class cholesterol‐lowering small interfering RNA (siRNA) that works through gene silencing. Even though it has been approved by NICE and a population health agreement is in place, uptake in general practice has been slow. This article examines the barriers to uptake and how these could be addressed.","PeriodicalId":88184,"journal":{"name":"The Prescriber","volume":"120 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The novel siRNA inclisiran and population health management\",\"authors\":\"L. Walker\",\"doi\":\"10.1002/psb.2037\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Inclisiran (Leqvio) is a first‐in‐class cholesterol‐lowering small interfering RNA (siRNA) that works through gene silencing. Even though it has been approved by NICE and a population health agreement is in place, uptake in general practice has been slow. This article examines the barriers to uptake and how these could be addressed.\",\"PeriodicalId\":88184,\"journal\":{\"name\":\"The Prescriber\",\"volume\":\"120 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Prescriber\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/psb.2037\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Prescriber","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/psb.2037","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The novel siRNA inclisiran and population health management
Inclisiran (Leqvio) is a first‐in‐class cholesterol‐lowering small interfering RNA (siRNA) that works through gene silencing. Even though it has been approved by NICE and a population health agreement is in place, uptake in general practice has been slow. This article examines the barriers to uptake and how these could be addressed.
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