点状黑斑:一种新的临床实体?

Cheng Tan, Wen‐yuan Zhu
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摘要

一名中国男性及其父亲成年后均出现弥散性大小不一的色斑和星状斑。经过广泛的评估,没有迹象表明系统性的介入。皮肤检查显示,大多数斑点呈星状或爪状,形状和大小各不相同。然而,作为一个整体,这些分散的病变有规律地穿插。病理改变包括明显的基底层色素沉着(黑眼线征),无黑色素细胞增生。真皮中可见噬黑细胞。我们提出了点状黑斑的诊断,并相信这是一个新的临床实体。
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Case report Pointillist melanotic macules: a new clinical entity?
A Chinese male and his father both presented disseminated, variably-sized and pigmented spots as well as stellate macules in their adulthood. No signs indicated a systemic involvement after extensive evaluation. Skin examina tion revealed that most macules were stellate or claw-like that differ from each other in shape and size. However, as a whole, these discrete lesions were interspersed regularly. Pathological changes included remarkable basilar lay er hyperpigmentation (black eye line sign) without proliferation of the melanocytes. Melanophages were noted in the dermis. We proposed the diagnosis of pointillist melanotic macules, and believe this is a new clinical entity.
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