使用Sugammadex治疗格林-巴利综合征1例报告

B. Tezcan, Demet Bölükbaşı, D. Kazancı, S. Turan, Gülseren Suer Kaya, A. Özgök
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引用次数: 3

摘要

Sugammadex包封罗库溴铵和维库溴铵并使其失活。它被用来逆转这些非去极化剂造成的神经肌肉阻滞。sugammadex在神经肌肉疾病患者中的安全性尚未确定。格林-巴利综合征(GBS)是一种以急性炎性多神经病变为特征的神经肌肉疾病。GBS患者可能表现出自主神经功能障碍、慢性疼痛、对神经肌肉阻滞剂的异常反应,并可能需要术后机械通气。我们报道一例慢性GBS患者行半结肠切除术,成功使用sugammadex逆转罗库溴铵。
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The Use of Sugammadex in a Patient With Guillain–Barre Syndrome: A Case Report
Sugammadex encapsulates and inactivates rocuronium and vecuronium. It is used to reverse neuromuscular blockade from these nondepolarizing agents. The safety of sugammadex in patients with neuromuscular disease has not been established. Guillain–Barre Syndrome (GBS) is a neuromuscular disease characterized by acute inflammatory polyneuropathy. Patients with GBS may exhibit autonomic dysfunction, chronic pain, abnormal reactions to neuromuscular blocking agents, and may require postoperative mechanical ventilation. We report the successful use of sugammadex to reverse rocuronium in a patient with chronic GBS, who presented for a hemicolectomy.
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