心肌收缩器要素形态学问题及研究展望

P. Kobeza
{"title":"心肌收缩器要素形态学问题及研究展望","authors":"P. Kobeza","doi":"10.26641/1997-9665.2021.2.68-76","DOIUrl":null,"url":null,"abstract":"Background. Over the past 50 years, specific methods for studying the ultrastructure of the heart have been rapidly developed. The complex interaction of various research methods makes it possible to more accurately form a representation of the spatial structure of the components of the myocardial contractile apparatus. Objective. To conduct a content analysis of the results of the study of the composition of the myocardial contractile apparatus. Conduct a broad analysis of literary references and form an understanding of the spatial structure of the components of the myocardial contractile apparatus in the prospect of research at different levels of cell organization. Methods. Processing of information sources was carried out by the method of complex meta-analysis of data analysis. Results. The morphological characteristics of the myocardial contractile apparatus include a number of broad profile elements. The system of composite elements of the contractile apparatus of cardiomyocytes is the most formed and developed in the structure of the cytoplasmic complex of organelles in the group of contractile cardiomyocytes. The complex of the contractile apparatus is represented by myofibrils, each of which consists of thousands of sarcomeres telophragm connected in series, containing actin (thin) and myosin (thick) myofilaments. The main methods for studying the contractile apparatus of the myocardium include how immunohistochemistry and transmission electron microscopy provide an understanding of the structure of components at various levels of organization of histoarchitectonics and ultrastructure of organelles.. The contractile apparatus of the myocardium includes species-specific organelles, which basically belong to a number of basic hardware systems of cardiomyocytes. Conclusion. Immunohistochemical methods should clearly show the localization of individual tipes of elements in the protein structure of the contractile apparatus of the myocardium, and therefore should include in the study methods the use of the following immunohistochemical markers that can show the configuration of thin and thick myofilaments. The results of analytical review and analysis of information sources on the characteristics of the components of the myofibrillar complex gives a choice of specific research methods and forms a more detailed understanding of the spatial organization of the morphology of the myocardial contractile apparatus.","PeriodicalId":19107,"journal":{"name":"Morphologia","volume":"79 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The morphology of the elements of the myocardial contractile apparatus question and research prospects\",\"authors\":\"P. Kobeza\",\"doi\":\"10.26641/1997-9665.2021.2.68-76\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background. Over the past 50 years, specific methods for studying the ultrastructure of the heart have been rapidly developed. The complex interaction of various research methods makes it possible to more accurately form a representation of the spatial structure of the components of the myocardial contractile apparatus. Objective. To conduct a content analysis of the results of the study of the composition of the myocardial contractile apparatus. Conduct a broad analysis of literary references and form an understanding of the spatial structure of the components of the myocardial contractile apparatus in the prospect of research at different levels of cell organization. Methods. Processing of information sources was carried out by the method of complex meta-analysis of data analysis. Results. The morphological characteristics of the myocardial contractile apparatus include a number of broad profile elements. The system of composite elements of the contractile apparatus of cardiomyocytes is the most formed and developed in the structure of the cytoplasmic complex of organelles in the group of contractile cardiomyocytes. The complex of the contractile apparatus is represented by myofibrils, each of which consists of thousands of sarcomeres telophragm connected in series, containing actin (thin) and myosin (thick) myofilaments. The main methods for studying the contractile apparatus of the myocardium include how immunohistochemistry and transmission electron microscopy provide an understanding of the structure of components at various levels of organization of histoarchitectonics and ultrastructure of organelles.. The contractile apparatus of the myocardium includes species-specific organelles, which basically belong to a number of basic hardware systems of cardiomyocytes. Conclusion. Immunohistochemical methods should clearly show the localization of individual tipes of elements in the protein structure of the contractile apparatus of the myocardium, and therefore should include in the study methods the use of the following immunohistochemical markers that can show the configuration of thin and thick myofilaments. The results of analytical review and analysis of information sources on the characteristics of the components of the myofibrillar complex gives a choice of specific research methods and forms a more detailed understanding of the spatial organization of the morphology of the myocardial contractile apparatus.\",\"PeriodicalId\":19107,\"journal\":{\"name\":\"Morphologia\",\"volume\":\"79 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-12-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Morphologia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.26641/1997-9665.2021.2.68-76\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Morphologia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26641/1997-9665.2021.2.68-76","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

背景。在过去的50年里,研究心脏超微结构的具体方法得到了迅速发展。各种研究方法的复杂相互作用使得更准确地形成心肌收缩器组成部分的空间结构的表征成为可能。目标。对心肌收缩器组成的研究结果进行内容分析。对文献资料进行广泛的分析,了解心肌收缩器各组成部分的空间结构,展望不同细胞组织水平的研究前景。方法。信息源处理采用数据分析的复杂元分析方法。结果。心肌收缩器的形态学特征包括许多宽剖面元素。心肌细胞收缩器的复合元件系统是收缩性心肌细胞群中细胞器胞质复合体结构中形成和发展最多的。收缩器官的复合体由肌原纤维代表,每一个肌原纤维都由成千上万的肌小纤维串联而成,含有肌动蛋白(细)和肌球蛋白(粗)肌丝。研究心肌收缩器官的主要方法包括免疫组织化学和透射电镜如何在组织结构和细胞器的超微结构的各个层次上提供组分的结构的理解。心肌的收缩器包括种类特异性的细胞器,它们基本上属于心肌细胞的一些基本硬件系统。结论。免疫组织化学方法应清楚地显示心肌收缩器蛋白质结构中单个类型元素的定位,因此在研究方法中应包括使用以下免疫组织化学标记物,这些标记物可以显示细肌丝和粗肌丝的结构。对肌原纤维复合体组成成分特征的分析回顾和信息源分析的结果,提供了具体研究方法的选择,并对心肌收缩器形态的空间组织形成了更详细的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
The morphology of the elements of the myocardial contractile apparatus question and research prospects
Background. Over the past 50 years, specific methods for studying the ultrastructure of the heart have been rapidly developed. The complex interaction of various research methods makes it possible to more accurately form a representation of the spatial structure of the components of the myocardial contractile apparatus. Objective. To conduct a content analysis of the results of the study of the composition of the myocardial contractile apparatus. Conduct a broad analysis of literary references and form an understanding of the spatial structure of the components of the myocardial contractile apparatus in the prospect of research at different levels of cell organization. Methods. Processing of information sources was carried out by the method of complex meta-analysis of data analysis. Results. The morphological characteristics of the myocardial contractile apparatus include a number of broad profile elements. The system of composite elements of the contractile apparatus of cardiomyocytes is the most formed and developed in the structure of the cytoplasmic complex of organelles in the group of contractile cardiomyocytes. The complex of the contractile apparatus is represented by myofibrils, each of which consists of thousands of sarcomeres telophragm connected in series, containing actin (thin) and myosin (thick) myofilaments. The main methods for studying the contractile apparatus of the myocardium include how immunohistochemistry and transmission electron microscopy provide an understanding of the structure of components at various levels of organization of histoarchitectonics and ultrastructure of organelles.. The contractile apparatus of the myocardium includes species-specific organelles, which basically belong to a number of basic hardware systems of cardiomyocytes. Conclusion. Immunohistochemical methods should clearly show the localization of individual tipes of elements in the protein structure of the contractile apparatus of the myocardium, and therefore should include in the study methods the use of the following immunohistochemical markers that can show the configuration of thin and thick myofilaments. The results of analytical review and analysis of information sources on the characteristics of the components of the myofibrillar complex gives a choice of specific research methods and forms a more detailed understanding of the spatial organization of the morphology of the myocardial contractile apparatus.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Morphological characteristic of premature infants’s kidneys with opened Ductus Arteriosis (by the autopsy). Analysis of the malignant ovarian tumors incidence in the Sumy region in 2014-2018. Pancreatic stellate cells: the top managers of the pancreatic tumor microenvironment. Histology and Cell Biology: An Introduction to Pathology 5th Edition 2020 To the anniversary of Professor Antonina Mykhailivna Yashchenko
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1