白参叶提取物体外自由基清除能力的研究

Priyanka J., S. I., N. R
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摘要

植物是各种植物化学物质的储存库,给人体带来更多的健康益处。我们的祖先在传统民间医学中广泛使用它们。这些植物化学物质的主要优点是它们可以用来治疗各种疾病,几乎没有副作用。自由基通过对细胞造成损伤,在各种疾病中起着重要作用。抗氧化剂在保护细胞免受损伤和减少自由基介导的增加氧化剂产生的有害后果方面起着广泛的作用。植物含有许多酶和非酶抗氧化剂,对这些疾病有更好的效果。本研究的主要目的是分析白菖蒲叶不同溶剂提取物的抗氧化能力。对白参叶提取物的各种溶剂“甲醇、乙酸乙酯、苯、乙醇、氯仿、石油醚、丙酮、水”进行了“DPPH、ABTS、羟基自由基、还原力、一氧化氮测定”等自由基清除试验。随着浓度的增加,所测试的提取物均表现出显著的自由基清除作用。所以这些来自植物的抗氧化化合物可以作为市场上可用的合成抗氧化剂的替代品。
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In Vitro Free Radical Scavenging Potential of Tabebuia pallida Leaf Extracts
Plants are the reservoir of various phytochemicals that gives more health benefits to the human body. They are widely used by our ancestors in traditional folk medicine. The major advantage of these phytochemicals is that they can be used to cure various diseases with little or no side effects. Free radicals play a major role in various disease conditions by causing damage to the cells. Antioxidants contribute an extensive part in defending the cells against damage and reduce the deleterious consequence of the free radicals mediated increased oxidant production. Plants contain a number of enzymic and non-enzymic antioxidants which render a better effect against these ailments. The main objective of the present study is to nalyse the antioxidant potential of various solvent extracts of Tabebuia pallida leaf. Free radical scavenging assays like, “DPPH, ABTS, hydroxyl radical, reducing power and nitric oxide assays’’, for the various solvents ``methanol, ethyl acetate, benzene, ethanol, chloroform, petroleum ether, acetone and water” of the leaf extracts of Tabebuia pallida were performed. All the extracts tested exhibit a remarkable radical scavenging effect as the concentration increases. So these antioxidant compounds from plant origin can be used as an alternative for the synthetic antioxidants that are available in the market.
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