抗菌菌sp中抗真菌和抗紫外线的潜在生物活性

Enjelika Polimba Sahuma, Deiske A. Sumilat, Veibe Warow, F. Losung, E. Angkouw, Okstan Kalesaran
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引用次数: 1

摘要

海鞘产生抑制微生物生长的生物活性化合物。在生物医学领域,海鞘也因其潜在的次级代谢物而闻名。本研究旨在获得海鞘共生体Eudistoma sp.的分离株,测定其对试验真菌白色念珠菌的抑菌活性,并测定其抗紫外线活性。采用乙酸乙酯溶剂浸取法提取海鞘共生体真菌,并用试验真菌白色念珠菌进行抑菌活性测定。抑菌活性试验结果表明,afbn5b的抑菌带直径为9 mm。这种共生真菌可以说是一种有潜力的抗真菌药物。用分光光度计测定与海ascidia Eudistoma sp.共生真菌的抗紫外线活性,结果表明,海ascidia Eudistoma sp.提取样品在UV-B (λ 290 ~ 320 nm)处的吸光度为3.8,与UV-A (λ 370 ~ 400 nm)相比,吸收值为0.38,仍然属于中等。关键词:海ascidia, Eudistoma sp.,共生菌,抗真菌,抗紫外线
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POTENSI BIOAKTIVITAS ANTI JAMUR DAN ANTI-UV DARI ISOLAT JAMUR SIMBION PADA ASCIDIA Eudistoma sp
Ascidia Eudistoma sp. produce bioactive compounds that can inhibit the growth of microorganisms. Ascidians are also known for their potential secondary metabolites in the biomedical world. This study aimed to obtain isolates of the ascidia symbiont Eudistoma sp., determine the antifungal activity against the test fungus Candida albicans, and determine the anti-UV activity of the symbiont Eudistoma sp. The ascidia symbiont fungus was extracted using maceration method with ethyl acetate solvent and tested for antifungal activity using the test fungus Candida albicans. The antifungal activity test results showed that the diameter of the AFBN 5b inhibition zone of 9 mm. The symbiont fungus can be said to have potential as an antifungal drug.  Testing the anti-UV activity of fungi in symbiosis with ascidia Eudistoma sp. using a spectrophotometer showed that the extract sample of the ascida symbiont fungus could produce an absorption at UV-B (λ 290–320 nm) of 3.8 absorbance and when compared to UV-A (λ 370–400 nm) an absorption value of 0.38 was obtained and is still classified as moderate Keywords: Ascidia, Eudistoma sp., symbionts, Antifungal and Anti-UV
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