结直肠癌患者AKT2和COX2突变的临床预后

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摘要

癌症已成为世界上最致命的疾病之一。据估计,2018年新增癌症病例为1810万例。结直肠癌(colorectal cancer, CRC)是世界范围内男性第三大常见癌症,女性第二常见癌症[1]。西方人群的发病率为5%至6%,如果有一级亲属被诊断患有此病,发病率可增加至15%至30%。在像Lynch综合征这样的遗传性易感性癌症综合征中,它可以增长到80%[2]。
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Clinical Prognosis of AKT2 and COX2 Mutation on Colorectal Cancer
Cancer has become one of the most mortal diseases in the world. It was estimated in 2018 18.1 millions new cancer cases. The colorectal cancer (CRC) is the third most common type of cancer in men and the second in women around the world [1]. The incidence risk in the occidental population is 5% to 6%, and it can increase to 15% to 30% when a first degree relative has the diagnoses. In hereditary predisposition cancer syndrome like the Lynch syndrome it can grow up to 80% [2].
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