正宗的意大利历史化妆品滑石粉样品分析-进一步证明缺乏癌症风险

E. Ilgren, C. Sartorio, J. Hoskins
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引用次数: 8

摘要

来自意大利西北部皮涅罗罗矿的意大利滑石粉以其极高的纯度而闻名。对这些矿山进行的几项历史调查表明,寄主岩石中有极少量的透闪石偶尔会进入开采的矿石中。然而,对皮涅罗罗矿工和磨坊主进行的60多年的流行病学研究未能证明有任何伴随的癌症风险,并表明这种微量透闪石污染没有生物学意义。关于1975年以前生产的意大利Pinerolo化妆品滑石粉被石棉(主要是透闪石)污染的说法很难反驳,因为缺乏商业产品的真实历史样本。我们现在描述最近发现的一个真实的历史样本的分析结果。对该材料的样品分析显示,只有少数非石棉类型的透闪石纤维——根据对该滑石矿床的历史(1975年以前)研究讨论了这一发现:没有检测到蛇纹石(温石棉)或角闪石纤维。滑石样品中透闪石纤维的数值浓度为3.687 x 106纤维/克,对应的质量浓度为0.722百万分之一。
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Analysis of an Authentic Historical Italian Cosmetic Talc Sample – Further Evidence for the Lack of Cancer Risk
Italian talc from the Pinerolo Mines in North West Italy is known for its extreme purity. Several historical investigations of these mines have demonstrated very small amounts of tremolite in the host rock that occasionally found their way into the mined ore. However, more than sixty years of epidemiological studies of the Pinerolo miners and millers have failed to demonstrate any attendant cancer risk and show that this trace tremolite contamination is of no biological significance.Claims made that the Pinerolo Italian cosmetic talc produced prior to 1975 were contaminated with asbestos, principally tremolite, have been difficult to refute given the lack of authentic historical samples of commercial products. We now describe the analytical findings of a recently discovered authentic historical sample.Sample analyses of this material showed only a few non-asbestiform tremolite fibres - a finding discussed in the light of the historical (pre-1975) studies of this talc deposit: no serpentine (chrysotile) or amphibole fibres were detected.The numerical concentration of tremolite fibres in the talc sample was 3.687 x 106 fibres/gram, corresponding to a mass concentration of 0.722 parts per million.
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