{"title":"胆碱解药在抗胆碱酯酶中毒治疗中的应用。3季铵化及阴离子功能改变对胆碱解毒剂效力治疗沙林中毒的影响。","authors":"I. W. Coleman, P. E. Little, R. Bannard","doi":"10.1139/O63-277","DOIUrl":null,"url":null,"abstract":"Twenty-one quaternary ammonium salts of cholinolytic drugs have been assessed for potency against Sarin poisoning in mice and rats in a treatment using N-methylpyridinium-2-aldoxime methanesulphona...","PeriodicalId":9531,"journal":{"name":"Canadian journal of biochemistry and physiology","volume":"2 1","pages":"2479-91"},"PeriodicalIF":0.0000,"publicationDate":"1963-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"11","resultStr":"{\"title\":\"CHOLINOLYTICS IN THE TREATMENT OF ANTICHOLINESTERASE POISONING. III. THE EFFECTS OF QUATERNIZATION AND ALTERATION OF ANIONIC FUNCTION OF THE POTENCY OF CHOLINOLYTICS IN THE TREATMENT OF SARIN POISONING.\",\"authors\":\"I. W. Coleman, P. E. Little, R. Bannard\",\"doi\":\"10.1139/O63-277\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Twenty-one quaternary ammonium salts of cholinolytic drugs have been assessed for potency against Sarin poisoning in mice and rats in a treatment using N-methylpyridinium-2-aldoxime methanesulphona...\",\"PeriodicalId\":9531,\"journal\":{\"name\":\"Canadian journal of biochemistry and physiology\",\"volume\":\"2 1\",\"pages\":\"2479-91\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1963-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"11\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Canadian journal of biochemistry and physiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1139/O63-277\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Canadian journal of biochemistry and physiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1139/O63-277","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
CHOLINOLYTICS IN THE TREATMENT OF ANTICHOLINESTERASE POISONING. III. THE EFFECTS OF QUATERNIZATION AND ALTERATION OF ANIONIC FUNCTION OF THE POTENCY OF CHOLINOLYTICS IN THE TREATMENT OF SARIN POISONING.
Twenty-one quaternary ammonium salts of cholinolytic drugs have been assessed for potency against Sarin poisoning in mice and rats in a treatment using N-methylpyridinium-2-aldoxime methanesulphona...
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