迷迭香与洋甘菊对链脲佐菌素诱导的糖尿病大鼠抗糖尿病活性的比较评价

M. Emam
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引用次数: 49

摘要

中药制剂在糖尿病、癌症和肝脏疾病的治疗中越来越重要,因为目前的治疗方法存在危险的副作用。特别是糖尿病可以通过对抗疗法和草药来控制。比较了迷迭香叶水提取物和洋甘菊叶水提取物对链脲佐菌素诱导的糖尿病大鼠的抗糖尿病作用。血清:空腹血糖及总蛋白等生化指标;碳水化合物水解酶;α -淀粉酶,总抗氧化能力,肝脏脂肪变性;测定总胆固醇、甘油三酯,剂量为200 mg/kg体重,持续21天。与对照大鼠相比,糖尿病大鼠的血糖水平显著降低(p<0.001),体重增加,其他生化指标明显改善。与对照大鼠相比,糖尿病大鼠的血糖水平显著降低(p<0.001),体重增加,正常细胞发生变化。
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Comparative evaluation of antidiabetic activity of Rosmarinus officinalis L. and Chamomile recutita in streptozotocin induced diabetic rats
Herbal formulations are getting more importance in the treatment of diabetes, cancer and hepatic disorder because of the hazardous adverse effects of the current therapy. Especially diabetes can be controlled by Allopathic medicine as well as Herbal medicine. A comparison was made between the antidiabetic activities of water extracts of leaves of Rosmarinus Officinalist and Chamomile recutitain Streptozotocin- induced diabetic rats. Serum Fasting blood glucose and other biochemical parameters such as total protein; carbohydrate hydrolyzing enzyme; α – amylase, total antioxidant capacity, liversteoteosis; total cholesterol, Triacylglycerol, were determined at the dose 200 mg/kg body weight for 21 days. There is a significant increase decrease in serum fasting blood glucose (p<0.001) , increase in body weight and improvement in the other biochemical parameters with treatment of herbal formulations which altered in diabetic rats There was a significant decrease in serum glucose level (p<0.001), increase in body weight and changes in normal cells was observed with treatment of the above mentioned extracts which altered in diabetic rats as compared to the control rats standard.
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