白香蕉象鼻虫提取物凝胶制剂(Musa acuminafe, sp)对褐家鼠烧伤愈合的影响

IF 2.9 4区 医学 Q2 PHARMACOLOGY & PHARMACY Journal of Pharmacy and Pharmaceutical Sciences Pub Date : 2023-07-13 DOI:10.36490/journal-jps.com.v6i3.184
Martina G. Laloan, Douglas N. Pareta, Selvana S. Tulandi, Yessie K. Lengkey, C. N. Sambou
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引用次数: 0

摘要

天然财富中有多种草本植物,其中包括有药用功效的植物。传统医学,是一种通常用作传统医学的成分或草药,用于加速疾病的愈合,用于加速伤口愈合的植物之一是白色goroho香蕉象鼻虫(Musa acuminafe, sp)。本研究旨在确定香蕉象鼻虫凝胶制剂对褐家鼠烧伤愈合的有效性。实验动物为15只大鼠。用金属硬币在老鼠的背部做了一个2.5厘米的烧伤。本研究采用的方法是实验室实验的形式。本研究采用完全随机设计(RAL),共5个处理,包括1个阴性对照,1个阳性对照(生物胎盘素),3个分层浓度,即5%浓度凝胶、10%浓度凝胶和15%浓度凝胶,每个重复3次。治疗持续14天。在此基础上测定大鼠创面直径的结果表明,香蕉象鼻虫提取物凝胶浓度为15%时的愈合效果优于其他提取物。
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Test of the effectiveness of white goroho banana weevil extract gel preparation (Musa acuminafe, sp) against the healing of white rat burns (Rattus nornvegicus)
Natural wealth has a variety of herbal plants, plants that are included in it efficacious as medicine. Traditional medicine, is an ingredient or herb that is usually used as traditional medicine and is used to accelerate the healing of diseases, one of the plants used to accelerate wound healing is the white goroho banana weevil (Musa acuminafe, sp). This study aimed to determine the effectiveness of banana weevil gel preparations against healing burns in white rats (Rattus norvegicus). The test animals used were 15 rats. A burn of 2.5 cm was made on the back of the mouse using metal coins. The method used in this study is in the form of laboratory experiments. This study used a Complete Randomized Design (RAL) consisting of 5 treatments, including 1 negative control, 1 positive control (bioplacenton), and 3 stratified concentrations, namely 5% concentration gel, 10% concentration gel and 15% concentration gel with 3 repetitions each. The treatment is carried out for 14 days. The results of measuring wound diameter in rats based on the results showed that banana weevil extract gel concentration of 15% provided a healing effect more effective than other extracts.
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来源期刊
CiteScore
6.90
自引率
0.00%
发文量
29
审稿时长
6-12 weeks
期刊介绍: The Journal of Pharmacy and Pharmaceutical Sciences (JPPS) is the official journal of the Canadian Society for Pharmaceutical Sciences. JPPS is a broad-spectrum, peer-reviewed, international pharmaceutical journal circulated electronically via the World Wide Web. Subscription to JPPS is free of charge. Articles will appear individually as soon as they are accepted and are ready for circulation.
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