青豆和扁豆芽对脂肪肝大鼠的生物学和生化影响

A. Gadallah, Alia Atia, Maymona El-Khlefa, Adel Badr
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摘要

作为最常见的慢性肝病之一,脂肪肝经常伴有其他代谢紊乱,如肥胖、胰岛素抵抗、高血压、血脂异常、脂肪代谢不良和心血管疾病的风险增加。豆芽是抗氧化剂、必需氨基酸和各种健康维生素和矿物质的重要来源。本研究选用30只白化大鼠。他们被分成6组;第一组为阴性对照组,饲喂标准日粮,其余各组饲喂高脂日粮诱导脂肪肝。其余大鼠分为4组,分别饲喂5%和10%的扁豆芽和豌豆芽28 d。其中一人仍然患有脂肪肝,并被给予基础饮食作为阳性对照组。豌豆和扁豆芽的化学成分及总酚和类黄酮含量。此外,还对增重(BWG)、采食量(FI)、饲料效率(FER)、肾脏和肝脏功能、血糖水平、胰岛素激素、脂质过氧化(MDA)水平和抗氧化酶水平进行了估计。结果表明,与扁豆芽相比,豌豆芽对所研究的参数有更大的积极影响;10%的水平明显高于5%的值。因此,豌豆芽和扁豆芽是治疗脂肪肝最广泛和最有效的药物。
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Biological and Biochemical Effect of Green Peas and Lentils Sprouts on Rats with Fatty Liver
ne of the most prevalent chronic liver illnesses, fatty liver is frequently accompanied by other metabolic disorders such as obesity, insulin resistance, hypertension, dyslipidemia, poor fat metabolism, and an elevated risk of cardiovascular disease. Sprouts are a great source of antioxidants, necessary amino acids, and a variety of healthy vitamins and minerals. For this study, 30 albino rats were employed. They were split into 6 groups; the first group served as a negative control group and was fed a standard diet, while the other groups were provided a high-fat diet to induce fatty liver. The remaining rats were divided into four groups and fed 5 and 10% of lentil and pea sprouts for 28 days. One of them was still suffering from fatty liver and was administered a base diet as a positive control group. T he chemical build and total phenolic and flavonoid content of pea and lentil sprouts. Additionally, estimates were made for body weight gain (BWG), feed intake (FI), the feed efficiency ratio (FER), kidney and liver functions, blood sugar levels, insulin hormones, and the levels of lipid peroxidation (MDA), and antioxidant enzymes. The findings demonstrated that, in comparison to lentil sprouts, pea sprouts had a greater positive impact on the investigated parameters; the level of 10% was noticeably higher than the value of 5%. Therefore, sprouts of peas and lentils are the most widely prescribed and the most effective agents for improving fatty liver.
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