视蛋白vs视蛋白:生物技术应用的新材料

E. Alfinito, L. Reggiani
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引用次数: 16

摘要

由于需要满足早期检测、低侵入性和低成本价值的新诊断方法,生物集成设备,特别是生物传感器的使用正成为技术研究的方向。实现这一目标所需的知识范围很广,从生物化学到电子学,并在电子学的一个新兴分支——蛋白质\textit{电子学中}得到了总结。蛋白电子学在这里被应用于对来自1型和2型视蛋白的电反应进行比较分析。特别是,该方法被用于对最近发现的视蛋白家族的早期研究,即蓝光激活的变形视紫红质(BPRs)。结果揭示了两个家族的蛋白质之间一些有趣和意想不到的相似之处,这表明全球电反应与阶级身份并不严格相关。
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Opsin vs opsin: new materials for biotechnological applications
The need of new diagnostic methods satisfying, as an early detection, a low invasive procedure and a cost-efficient value, is orienting the technological research toward the use of bio-integrated devices, in particular bio-sensors. The set of know-why necessary to achieve this goal is wide, from biochemistry to electronics and is summarized in an emerging branch of electronics, called \textit{proteotronics}. Proteotronics is here here applied to state a comparative analysis of the electrical responses coming from type-1 and type-2 opsins. In particular, the procedure is used as an early investigation of a recently discovered family of opsins, the proteorhodopsins activated by blue light, BPRs. The results reveal some interesting and unexpected similarities between proteins of the two families, suggesting the global electrical response are not strictly linked to the class identity.
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