天然多酚与中枢神经系统疾病的关系综述

A. Singh
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摘要

多酚是植物中广泛存在的一种成分,它提供了一种抵御各种应激因素的屏障。它们自然存在于我们的饮食中,它们的摄入量与压力导致的有害中枢神经系统相关变量呈负相关。茶、咖啡、蔬菜、可可等都是多酚的丰富来源。可可也是一种非常丰富的多酚来源。可可中的黄酮-3-醇可以降低中风、心肌梗死、糖尿病的风险,还可以降低依赖血流的内皮脂质系统性炎症和对血压免疫的胰岛素。心脏代谢安全性也与类黄酮、槲皮素和二苯乙烯白藜芦醇有关。类黄酮和其他多酚类物质是包罗一切的植物化学物质,对它们的家园植物起着许多生物功能。多酚饮食摄入被认为可以降低氧化应激。以饮食的形式摄入多酚可以减少氧化应激。氧化应激的减少可以抑制相关神经退行性疾病的风险,如阿尔茨海默病(AD)、中风、多发性硬化症(MS)、帕金森病(PD)和亨廷顿病(HD)。因此,分析表明多酚对人类大脑活动有益,本文通过讨论最新的机制假设来描述这些影响。
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Natural polyphenols in central nervous system disorders – A review
Polyphenols are widespread constituent present in plants that provide a shield against various stress-causing factors. They are naturally present in our diet and their consumption is inversely associated with harmful central nervous system-related variables due to stress. The rich source of polyphenol is tea, coffee, vegetables, cocoa, etc. Cocoa is also a very rich source of polyphenol origin. Flavon-3-ols, cocoa reduces of the risk of stroke, myocardial infarction, diabetics, as well as healthier systematic inflammation in endothelial lipid dependent on blood flow and the insulin immune to blood pressure. The cardiometabolic safety was also linked to flavonoids quercetin and stilbene resveratrol. Flavonoids and other polyphenols are all-encompassing plant chemicals that perform a number of bionomic functions for their home plant. Polyphenol dietary consumption is known for decreased oxidative stress. Intake of polyphenols in the form of diet well known for reduced oxidative stress. Reduced oxidative stress causes the suppression of the risk of associated neurodegenerative diseases, such as, Alzheimer’s disease (AD), stroke, multiple sclerosis (MS), Parkinson’s disease (PD) and Huntington’s disease (HD). Consequently, the analysis indicates that polyphenol beneficial effects on human brain activity and this review describe these implications by discussing the latest mechanistic hypothesis.
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