{"title":"自体结膜细胞移植在泪道重建中的疗效观察","authors":"Miaoying Zhang, J. Zhong","doi":"10.3760/CMA.J.ISSN.2095-1477.2019.12.007","DOIUrl":null,"url":null,"abstract":"Objective \nTo evaluate the clinical efficacy of cultured autologous conjunctival cells transplantation in lacrimal duct reconstruction. \n \n \nMethods \nA prospective study. Total of 55 eyes of 52 cases with severe obstruction of lacrimal duct and absence or atrophy of lacrimal sac from Jun. 2016 to Jun. 2018 were enrolled in this study. They were treated with cultured autologous conjunctival cells transplantation in lacrimal duct reconstruction. The clinical efficacy was observed after operation. \n \n \nResults \nAfter operation, 41 eyes (74.54%) were cured, improved in 12 eyes (21.82%) and ineffective in 2 eyes (3.64%). The total effective rate was 96.36%. \n \n \nConclusion \nThe reconstruction of lacrimal duct with cultured conjunctival cells transplantation is effective. \n \n \nKey words: \nConjunctival cells, autologous, culture, in vitro; Reconstruction, lacrimal passage; Obstruction, lacrimal passage, severe; Missing, lacrimal sac; Atrophy, lacrimal sac","PeriodicalId":10126,"journal":{"name":"中华眼外伤职业眼病杂志","volume":"45 1","pages":"910-913"},"PeriodicalIF":0.0000,"publicationDate":"2019-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Efficacy of cultured autologous conjunctival cells transplantation in lacrimal duct reconstruction\",\"authors\":\"Miaoying Zhang, J. Zhong\",\"doi\":\"10.3760/CMA.J.ISSN.2095-1477.2019.12.007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective \\nTo evaluate the clinical efficacy of cultured autologous conjunctival cells transplantation in lacrimal duct reconstruction. \\n \\n \\nMethods \\nA prospective study. Total of 55 eyes of 52 cases with severe obstruction of lacrimal duct and absence or atrophy of lacrimal sac from Jun. 2016 to Jun. 2018 were enrolled in this study. They were treated with cultured autologous conjunctival cells transplantation in lacrimal duct reconstruction. The clinical efficacy was observed after operation. \\n \\n \\nResults \\nAfter operation, 41 eyes (74.54%) were cured, improved in 12 eyes (21.82%) and ineffective in 2 eyes (3.64%). The total effective rate was 96.36%. \\n \\n \\nConclusion \\nThe reconstruction of lacrimal duct with cultured conjunctival cells transplantation is effective. \\n \\n \\nKey words: \\nConjunctival cells, autologous, culture, in vitro; Reconstruction, lacrimal passage; Obstruction, lacrimal passage, severe; Missing, lacrimal sac; Atrophy, lacrimal sac\",\"PeriodicalId\":10126,\"journal\":{\"name\":\"中华眼外伤职业眼病杂志\",\"volume\":\"45 1\",\"pages\":\"910-913\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-12-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中华眼外伤职业眼病杂志\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2019.12.007\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华眼外伤职业眼病杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2019.12.007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Efficacy of cultured autologous conjunctival cells transplantation in lacrimal duct reconstruction
Objective
To evaluate the clinical efficacy of cultured autologous conjunctival cells transplantation in lacrimal duct reconstruction.
Methods
A prospective study. Total of 55 eyes of 52 cases with severe obstruction of lacrimal duct and absence or atrophy of lacrimal sac from Jun. 2016 to Jun. 2018 were enrolled in this study. They were treated with cultured autologous conjunctival cells transplantation in lacrimal duct reconstruction. The clinical efficacy was observed after operation.
Results
After operation, 41 eyes (74.54%) were cured, improved in 12 eyes (21.82%) and ineffective in 2 eyes (3.64%). The total effective rate was 96.36%.
Conclusion
The reconstruction of lacrimal duct with cultured conjunctival cells transplantation is effective.
Key words:
Conjunctival cells, autologous, culture, in vitro; Reconstruction, lacrimal passage; Obstruction, lacrimal passage, severe; Missing, lacrimal sac; Atrophy, lacrimal sac
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