孟加拉国达卡孟加拉国卫生科学研究所(BIHS)总医院就诊的COVID-19患者全血细胞计数(CBC

Khaleda Ferdous, Md. Ashiqur Rahman, S. Islam, Sadia Tasnim, Tamima Ferdausi, Shohanur Rahaman, Md. Altap Hossen, Adiatuj Jahan Rimu
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摘要

严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)是导致2019冠状病毒病(COVID-19)的传染因子,这是一种传染病。自2019年12月在中国湖北武汉首次发现以来,疫情一直在持续。世界卫生组织估计,10月5日,全球可能有8亿人(或十分之一)感染COVID-19。截至2020年10月11日,已有107多万人死亡,3700多万例病例,遍及188个国家和地区;超过2570万患者已经康复。发烧、咳嗽、疲惫、呼吸短促或其他呼吸问题,以及味觉和嗅觉丧失是典型的症状。急性呼吸窘迫综合征(ARDS)可由细胞因子风暴、多器官衰竭、感染性休克和血凝块引起,可影响一些人,但大多数人只有中度症状。潜伏期可达1至14天。本研究的目的是观察孟加拉国COVID-19和非COVID-19患者的全血细胞计数。本研究采用描述性横断面研究。数据收集自孟加拉国卫生科学研究所(BIHS)总医院和孟加拉国卫生科学大学(BUHS)血液科。数据收集采用预测半结构化问卷。标准诊断方法是通过鼻咽拭子实时逆转录聚合酶链反应(RT-PCR)。结果显示,100例患者中,50%的患者呈Covid-19阳性,50%的患者呈阴性。对比Covid-19阳性和阴性的CBC结果显示Hb%几乎相同,Covid-19阳性患者的总计数略高于非Covid-19患者。阳性和阴性患者红细胞均在正常范围内。阳性患者血小板计数和PCV均低于阴性患者。阳性患者中性粒细胞明显升高。阳性患者淋巴细胞明显低于阴性患者。在这项研究中,男性受影响的比例为64%,女性为36%,因此男女比例为3:2。在50-70岁之间发现更多的阳性患者,在40-80岁之间有风险。根据本研究,可以得出结论,在临床上,中性粒细胞、淋巴细胞等细胞状态在COVID-19和非COVID-19患者中存在关联。
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Complete Blood Count (CBC) in COVID-19 Patients Attending at Bangladesh Institute of Health Sciences (BIHS) General Hospital, Dhaka, Bangladesh
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the infectious agent that causes Coronavirus Disease 2019 (COVID-19), a contagious illness. The epidemic has continued since it was first discovered in Wuhan, Hubei, China, in December 2019. The WHO estimated that 800 million people worldwide (or one in ten) may have COVID-19 infection on October 5. More than 1.07 million fatalities and 37 million cases have been documented as of October 11, 2020, spanning 188 nations and territories; more than 25.7 million patients have recovered. Fever, coughing, exhaustion, shortness of breath or other breathing issues, and a loss of taste and smell are typical symptoms. Acute respiratory distress syndrome (ARDS), which can be brought on by cytokine storm, multi-organ failure, septic shock, and blood clots, can affect some people while the majority only have moderate symptoms. One to fourteen days may pass during the incubation period. The aim of this study was to observe the Complete blood count in COVID-19 & Non COVID-19 Patients in Bangladesh. A descriptive cross-sectional study was conducted for the study. Data were collected from Bangladesh Institute of Health Sciences (BIHS) General Hospital and Hematology Department of Bangladesh University of Health Sciences (BUHS). A pretested semi-structured questionnaire was used for the data collection. The standard method of diagnosis is by real-time reverse transcription polymerase chain reaction (RT-PCR) from a nasopharyngeal swab. The results showed that, among 100 patients, 50% patient was Covid-19 positive &50% patient was negative. In comparison between Covid-19 positive & negative CBC result showing that Hb% remain almost same, total count is slightly increased in covid-19 positive patient than non-covid-19. RBC are found in Normal range for both positive and negative patients. Platelet count & PCV are lower in Covid-19 positive patient than negative patient. Neutrophil are significantly raised in Covid-19 positive patient. Lymphocytes are significantly decreased in Covid-19 positive patient than negative. In this study males are affected 64% & females are 36% so the ratio between male& female is 3:2. More positive patients were found in the age between 50-70 years & has risk among 40-80 years. According to this study, it can be concluded that there is an association among neutrophil, lymphocyte and other cell status in clinically in COVID-19 & non COVID-19 Patients.
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