卡纳塔克邦某三级医院肠球菌种类及抗生素谱资料分析

T. B. Naik, V. Mane, A. Upadhya
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摘要

背景:肠球菌以前被认为在健康人群中毒性较低,但由于它们能够在胃肠道长时间定植,这是耐药性发展的关键因素,并已成为主要的治疗障碍,因此它们最近成为重要的机会性病原体,特别是在住院患者中。目的:确定不同临床标本中分离的肠球菌种类。2. 目的:确定肠球菌的药敏模式。方法和材料:在卡纳塔克邦Shivamogga区的一家私立三级保健医院进行了一项横断面研究,使用了2014年1月至2014年12月期间从微生物学实验室登记处保存的尿液、血液、脓液、痰液和无菌体液等各种临床样本中分离出的肠球菌物种的二次数据。结果:66株肠球菌分离株中,尿中检出32株(48.48%),脓中检出22株(33.33%)。肠球菌以女性34例(51.51%)居多。粪肠球菌是最常见的分离物,共56例(84.84%)。所有菌株均对利奈唑胺和万古霉素敏感。对青霉素的耐药率最高,26例(76.47%)。结论:鉴于耐药性上升的大趋势和肠球菌种类的广泛发生,需要持续监测肠球菌的耐药性,以提出合适的治疗方案。
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An Analysis of Data of Enterococci Species and Its Antibiogram at a Tertiary Care Hospital in Karnataka
Background: Enterococci were previously thought to be less virulent in healthy people, but they have recently emerged as important opportunistic pathogens, particularly in hospitalized patients, due to their ability to colonize the gastrointestinal tract for long periods, which is a key factor in the development of drug resistance and has become a major treatment roadblock. Objectives: To determine the species of Enterococci isolated from different clinical samples. 2. To determine the antimicrobial susceptibility pattern of Enterococci species. Methods and Materials: A cross-sectional study was carried out at a private tertiary care hospital in the Shivamogga district of Karnataka, using secondary data of Enterococcal species isolated from various clinical samples such as urine, blood, pus, sputum, and sterile body fluids that were maintained in the Microbiology laboratory registers for a period of one year from January 2014 to December 2014. Results: Out of 66 enterococcal isolates from various clinical samples majority i.e. 32 (48.48%) were found in urine, followed by pus 22 (33.33%). The majority of Enterococcus was seen in females 34 (51.51%). Enterococcus faecalis was the most common isolate, accounting for 56 (84.84%) of the total. Sensitivity to Linezolid and Vancomycin was found in all of the isolates. Maximum resistance was seen against Penicillin i.e. 26 (76.47%). Conclusion: Given the general trend of rising drug resistance and the occurrence of a wide range of Enterococcus species, ongoing surveillance of antimicrobial resistance in enterococci is required to propose suitable therapy.
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