纳米治疗在结直肠癌治疗中的应用

Saloni Sharma, Gowthamarajan Kuppusamy, Parikshit Roy Chowdhury, Divya Pamu
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引用次数: 0

摘要

结直肠癌(CRC)是一种非常普遍和最常见的死亡原因。选择纳米治疗技术治疗结直肠癌是克服结直肠癌(CRC)的新兴策略之一。磁性纳米颗粒在这种情况下被采用,因为它们具有生物医学应用,如诊断成像、热处理和药物运输。有证据表明,在纳米颗粒表面使用各种化学物质,如配体,以突出与靶区域的肿瘤细胞的接触,以诱导有效的细胞毒性药物释放。本文将重点介绍目前在靶向磁性纳米颗粒治疗结直肠癌方面的突破,以及利用体外和体内能量电离辐射选择配体及其细胞靶点用于结直肠癌治疗。
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Nanotheranostic Approach for the management of colorectal cancer
Colorectal Cancer (CRC) is a highly prevalent and the most frequent reason for death. The choice of nanotheranostic technology for the management of colorectal cancer is one of the emerging strategies to overcome Colorectal Cancer (CRC). Magnetic nanoparticles are employed in this case because they have biomedical applications, such as diagnostic imaging, thermal treatment, and medication transport. There has been evidence of the usage of various chemicals on the surface of nano-particles, such as ligands, to highlight the contact with tumour cells at the target region in order to induce effective cytotoxic drug release. This review will highlight current breakthroughs in targeting magnetic nanoparticles against colorectal cancer, as well as the selection of ligands and their cellular targets with ionizing radiation employing in vitro and in vivo energies for Colorectal Cancer management.
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Nanoscience and Nanotechnology - Asia
Nanoscience and Nanotechnology - Asia Engineering-Engineering (all)
CiteScore
1.90
自引率
0.00%
发文量
35
期刊介绍: Nanoscience & Nanotechnology-Asia publishes expert reviews, original research articles, letters and guest edited issues on all the most recent advances in nanoscience and nanotechnology with an emphasis on research in Asia and Japan. All aspects of the field are represented including chemistry, physics, materials science, biology and engineering mainly covering the following; synthesis, characterization, assembly, theory, and simulation of nanostructures (nanomaterials and assemblies, nanodevices, nano-bubbles, nano-droplets, nanofluidics, and self-assembled structures), nanofabrication, nanobiotechnology, nanomedicine and methods and tools for nanoscience and nanotechnology.
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