木香花甲醇提取物的抗氧化和抗菌活性研究

A. Hamilton-Amachree, E. O. Odokwo
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引用次数: 0

摘要

对木香花部分甲醇提取物进行了化学和生物学分析。花卉部分采自巴耶尔萨州Ogbia地方政府区。花部分风干,研磨,在室温甲醇中提取。然后在压力下浓缩甲醇提取物混合物。对浓缩提取物MCL进行了定量的植物化学筛选、抗氧化和抗菌分析。定量分析结果显示,黄酮类化合物(59.444±0.000)、总皂苷(2.93±0.06)、酚类化合物(14.853±0.350)、单宁(6.638±0.051)、生物碱(3.72±0.02)、黄酮类化合物(59.444±0.000)。抗氧化活性随甲醇提取物浓度的增加而增加。在生物学上,花部分显示出对以下微生物菌株的活性:金黄色葡萄球菌、枯草芽孢杆菌、大肠杆菌、铜绿假单胞菌、伤寒沙门氏菌、白色念珠菌、肺炎克雷伯菌和镰刀菌,其中对金黄色葡萄球菌的活性最高。对大肠杆菌的抑菌活性最低。本研究确定了其植物结构、体外抗氧化和抗菌活性。
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Antioxidant and Antimicrobial Activities of Floral Methanolic Extract of Costus lucanisianus
The chemical and biological profiling of the methanolic extract of the floral part of Costus lucanisianus have been carried out. The floral part was collected from Ogbia Local Government Area of Bayelsa State. The floral part was air dried, grinded and extracted at room temperature in methanol. The methanol extract mixture was then concentrated under pressure. The concentrated extract, MCL was subjected to quantitative phytochemical screening, antioxidant and antimicrobial profiling. The result of the quantitative analysis showed the presence of phenols (14.853±0.350), tannins (6.638±0.051), alkaloids (3.72±0.02), flavonoids (59.444±0.000) and saponins (2.93±0.06). The antioxidant activity increases as the concentration of the methanolic extract increases. Biologically, the floral part has shown activities against the following strains of microbes: Staphylococcus aureus, Bacillus subtillis, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Candida albican, Klebsiela pneumonia, and Fusarium spp. with the highest activity observed against Staphylococcus aureus. The least antimicrobial activity was observed for Escherichia coli. The present study has established the phytoconstitution, in vitro antioxidant and antimicrobial activities.
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