研发Covid-19疫苗的努力:成功与障碍

Sachin Sharma, Shashank ., Amit Joshi, Manali Singh
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摘要

最近发现的SARS-CoV-2病毒粒子已引起全球流行,产生了社会、心理和经济后果。需要采取广泛的预防措施,如广泛诊断和严格隔离感染者,以避免继续传播;然而,落实这些遏制措施是一项巨大的努力。这种冠状病毒的持续传播凸显了在这一领域开展国际合作的重要性。如果COVID-19疫苗能够提供一定程度的免疫保护,封锁和社会隔离可能会得到缓解。目前,有许多疫苗可以通过产生免疫力来保护人们免受新型冠状病毒的侵害。病毒的生化特征见图1。与以往的COVID-19疫苗综述文章不同的是,本文评估了采用多种技术方法开发的现有疫苗的优缺点,以及多种蛋白质疫苗的安全性和有效性[1,2]。在疫苗制作之外,可能的障碍包括疫苗的可接受性、采购和分发以及全球实施。非典Covid-2
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Effort to Develop a Covid-19 Vaccine: Successes and Obstacles
The recently identified SARS-CoV-2 virion has caused a worldwide epidemic, producing sociological, psychological, and economic consequences. Extensive precautions, like as widespread diagnosis and strict segregation of infected persons, are required to avoid continued transmission; nevertheless, putting these containment methods in place is a massive endeavour. The ongoing spread of this coronavirus emphasises the significance of international cooperation in this area. Lockdowns and social separation could be eased if a COVID-19 vaccination delivers some level of immunological protection. At present, many vaccines are available, which can protect people from novel coronavirus by developing immunity. The biochemistry of the virus shown in Fig. 1. This article differs from previous COVID-19 vaccine review articles in that it evaluates the advantages and disadvantages of available vaccines developed by using diverse technical methods, and the safety and effectiveness of the many protein vaccines [1,2]. Outside of vaccine crafting, possible roadblocks include vaccination acceptability, procurement, & distribution, as well as global implementation. SARS Covid-2
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