{"title":"鱼类组织中奎尼丁药物的简单直接定量分析","authors":"Yuan-Chin Chen, H. Abdelhamid, Hui-Fen Wu","doi":"10.5478/MSL.2017.8.1.8","DOIUrl":null,"url":null,"abstract":"Analysis of quinidine for fish tissues using single drop microextraction (SDME) coupled with atmospheric pressure matrix assisted laser desorption/ionization mass spectrometry (AP-MALDI-MS) are reported. Optimization conditions; such as extraction solvent, extraction time, pH of the aqueous solution, salt additions (NaCl), stirring rate, matrix type and concentration are investigated. Linear dynamic range (μM), limit of detection, relative recovery%, and enrichment factor are 0.08-9.2, 0.05, 94.8±3.198.5±3.3%, 4.34±0.28-4.40±0.30, respectively. SDME-AP-MALDI-MS shows good intraday and interday reproducibility.","PeriodicalId":18238,"journal":{"name":"Mass Spectrometry Letters","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2017-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"7","resultStr":"{\"title\":\"Simple and Direct Quantitative Analysis for Quinidine Drug in Fish Tissues\",\"authors\":\"Yuan-Chin Chen, H. Abdelhamid, Hui-Fen Wu\",\"doi\":\"10.5478/MSL.2017.8.1.8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Analysis of quinidine for fish tissues using single drop microextraction (SDME) coupled with atmospheric pressure matrix assisted laser desorption/ionization mass spectrometry (AP-MALDI-MS) are reported. Optimization conditions; such as extraction solvent, extraction time, pH of the aqueous solution, salt additions (NaCl), stirring rate, matrix type and concentration are investigated. Linear dynamic range (μM), limit of detection, relative recovery%, and enrichment factor are 0.08-9.2, 0.05, 94.8±3.198.5±3.3%, 4.34±0.28-4.40±0.30, respectively. SDME-AP-MALDI-MS shows good intraday and interday reproducibility.\",\"PeriodicalId\":18238,\"journal\":{\"name\":\"Mass Spectrometry Letters\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2017-03-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"7\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Mass Spectrometry Letters\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5478/MSL.2017.8.1.8\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"SPECTROSCOPY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mass Spectrometry Letters","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5478/MSL.2017.8.1.8","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"SPECTROSCOPY","Score":null,"Total":0}
Simple and Direct Quantitative Analysis for Quinidine Drug in Fish Tissues
Analysis of quinidine for fish tissues using single drop microextraction (SDME) coupled with atmospheric pressure matrix assisted laser desorption/ionization mass spectrometry (AP-MALDI-MS) are reported. Optimization conditions; such as extraction solvent, extraction time, pH of the aqueous solution, salt additions (NaCl), stirring rate, matrix type and concentration are investigated. Linear dynamic range (μM), limit of detection, relative recovery%, and enrichment factor are 0.08-9.2, 0.05, 94.8±3.198.5±3.3%, 4.34±0.28-4.40±0.30, respectively. SDME-AP-MALDI-MS shows good intraday and interday reproducibility.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
