评估含有80%芦荟凝胶的局部输送系统作为慢性牙周炎刮治和牙根规划的辅助:一项临床研究

Prakash Singh, Manish Jain, V. Saxena, Vijayta Sharva, Meenakshi Boddun, N. Jain
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引用次数: 1

摘要

背景:近年来对替代医学领域的兴趣和进展促进了各种草药和天然产品在医学领域的多种用途。芦荟是一种具有多种益处的产品,在临床研究中具有相当大的重要性。本临床研究的重点是芦荟,并强调其特性时,作为药物在牙周袋。目的:本研究的目的是评估含有80%芦荟凝胶的局部给药系统用于慢性牙周炎的洗牙和牙根规划辅助治疗。目的:评价芦荟对牙龈炎、牙周炎的治疗作用,比较芦荟在试验部位应用前后抗氧化水平。材料与方法:本研究对30例牙周炎患者进行研究。采用裂口设计。GI、SBI、CPI、LOA和PD分别在基线、15天和1个月时记录。在基线记录所有指标后和用药前,整个患者立即用手器械进行刮治和根规划。用钝针注射器将芦荟凝胶注射到治疗试验部位选定牙齿周围的口袋中。对照场地只接受了尺度和根系规划。采集15例CP患者治疗前后的生物力学分析- gcf。用比色法和商用试剂盒测定总抗氧化状态。结果与结论:在本研究中,试验点与对照组GCF中抗氧化水平存在显著差异。试验点抗氧化水平显著升高,临床参数显著改善,应用芦荟2个月后,同时进行洗牙和根规划,而对照组抗氧化水平无显著变化。抗氧化剂与探针深度和附着损失呈极显著正相关。*通信:Vijayta Sharva,读者,公共卫生牙科,人民牙科学院,博帕尔,中央邦,印度,电话:9827563977;电子邮件:vijaytasharva@gmail.com
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Evaluation of local – delivery system containing 80% aloe vera gel used as an adjunct to scaling and root planning in chronic periodontitis: A clinical study
Background: Recent interest and advances in the field of alternative medicine has promoted the use of various herbal and natural products for multiple uses in the field of medicine. Aloe vera is one such product exhibiting multiple benefits and has gained considerable importance in clinical research. This clinical study focuses on Aloe vera and highlights its property when used as a medicament in the periodontal pocket. Aim: The aim of this study was Evaluation of local – delivery system containing 80% aloevera gel used as an adjunct to scaling and root planning in chronic periodontitis. Objective: To evaluate the efficacy of Aloevera in reduction of gingivitis and periodontits and to compare the antioxidant level before and after alovera application on test site. Material and method: Present study was conducted among 30 patients having periodontitis. Split mouth design was used. GI, SBI, CPI, LOA & PD were recorded at baseline, 15 days & at 1 month. Immediately after recording all the indices at baseline and prior to drug application, the entire patient underwent scaling and root planning with hand instrument. The aloe vera gel was injected into the pockets with a syringe with blunt needle around the selected teeth in the treatment test site. The control site received only scaling and root planning. Biomechanical analysis-GCF was collected from 15 CP patients before and after treatment. Total antioxidant status was determined using colorimetric method and commercial kits. Result & conclusion: In the present study there was a significant difference in antioxidant level in GCF between test site and control site. Test site showed significant increase in antioxidant level and significant improvement in clinical parameter 2 month after application of aloe vera along with scaling and root planning while on control site there was no significant change in antioxidant level. There was strong significant positive correlation of antioxidant with probing depth and attachment loss. *Correspondence to: Vijayta Sharva, Reader, Public Health Dentistry, Peoples Dental Academy, Bhopal, Madhya Pradesh, India, Tel: 9827563977; E-mail: vijaytasharva@gmail.com
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