反复呼吸道感染患儿血清对多糖的抗体反应

Alberto López-Yap, A. Abdelnour, B. Lomonte, Ó. Porras
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引用次数: 3

摘要

摘要:我们使用酶联免疫吸附测定法对反复上呼吸道感染且血清免疫球蛋白水平正常的儿童(15个月及以上)进行特异性多糖免疫缺陷检测。结果显示,在接种Act-HIB疫苗的12名患者中,有1名患者没有产生b型流感嗜血杆菌的特异性抗体,这表明这种免疫缺陷存在于哥斯达黎加儿童中。
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Serum Antibody Response to Polysaccharides in Children with Recurrent Respiratory Tract Infections
ABSTRACT We evaluated children (15-months old and older) with recurrent upper respiratory tract infections and normal levels of immunoglobulins in serum for specific polysaccharide immunodeficiency using an enzyme-linked immunosorbent assay method. Results showed that of 12 patients vaccinated with Act-HIB vaccine, one did not develop specific antibodies to Haemophilus influenzae type b, demonstrating that such immunodeficiency is present in Costa Rican children.
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