大疱性类天疱疮:与多方面的koebner现象有关

S. Nayak, Shukriti Shenoi, S. Prabhu, R. Rao
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摘要

Koebner现象(KP)或同构现象通常有助于某些疾病的诊断,并经常反映疾病的活动性。虽然常报道与牛皮癣,白癜风,和扁平苔藓,KP已偶尔报道与其他条件。大疱性类天疱疮与此有罕见的关联,我们报告一个病例与抓挠是刺激因素。一名50岁女性,无合并症,表现为全身发痒充满液体的病变,持续15天。检查显示前臂大泡和小泡广泛分布,有线状大泡。组织病理学和免疫荧光研究证实为大疱性类天疱疮。KP一般由机械性创伤、治疗、皮肤病或反应引起。大疱性类天疱疮的KP很少被报道,在Boyd和Nelder分类的第IV类中被提及。本例患者大疱的线性特征提示划伤是KP的诱发因素,据我们所知尚未有相关报道。
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Bullous pemphigoid: Associating with the multifaceted phenomenon of koebner
Koebner phenomenon (KP) or isomorphic phenomenon often helps in diagnosis of certain conditions and often reflects disease activity. Although commonly reported with psoriasis, vitiligo, and lichen planus, KP has been occasional reported with other conditions. Bullous pemphigoid has a rare association with this and we report a case with scratching being the inciting factor. A 50-year-old female with no comorbidities presented with itchy fluid-filled lesions all over the body for 15 days. Examination showed generalized distribution of bullae and vesicles with linear bulla on the forearms. Histopathology and immunofluorescence studies were conclusive of bullous pemphigoid. KP has been reported in general due to mechanical trauma, therapy, dermatoses, or reactions. KP in bullous pemphigoid is rarely reported and it is mentioned in the category IV of Boyd and Nelder classification. The linear nature of bulla in our patient was suggestive of scratching being the inciting factor for KP, which has not been reported to the best of our knowledge.
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