透明质酸填充充血剂作为下眼睑瘢痕外翻的暂时性组织扩张剂

Moisés Enghelberg, L. Michaelos, C. Ionescu, Tatiana Stingu, D. Georgescu
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引用次数: 2

摘要

我们描述了治疗下眼睑瘢痕性外翻在一个24岁的男性使用填充透明质酸(HA)。一毫升的Juvederm Voluma被直接注射到每个下眼睑的皮肤下,形成一个大泡泡。5个月后用透明质酸酶(750 iu /侧)溶解填充物,获得良好稳定的功能和美容效果。填充物就位后,MRD-2改善2.4 mm,在透明质酸酶溶解填充物6个月后下降到1.72 mm。这导致了角膜暴露的体征和症状的完全解决。迄今为止,已有低密度血凝素注射用于治疗老年患者和板层状鱼鳞病婴儿的瘢痕性外翻的报道。在这些情况下,HA被注入并留在原地自行溶解。我们的病例是第一例直接在皮肤下注射具有高G′性质的透明质酸的报道,一旦组织扩张,透明质酸酶就会完全溶解。
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VOLUMIZING HYALURONIC ACID FILLER AS TEMPORARY TISSUE EXPANDER IN LOWER EYELID CICATRICIAL ECTROPION
We describe the treatment of lower eyelid cicatricial ectropion in a 24 year old male using volumizing hyaluronic acid (HA) filler. One milliliter of Juvederm Voluma was injected directly under the skin in each lower eyelid to create a large bubble.  The filler was dissolved with hyaluronidase (750 I.U. / side) 5 months later, achieving an excellent and stable functional and cosmetic result. There was a 2.4 mm improvement in MRD-2 with the filler in place which decreased to 1.72 mm at 6 months after filler dissolution with hyaluronidase. This resulted in complete resolution of the signs and symptoms of corneal exposure. To date, there have been reports of low density HA injection for the treatment of cicatricial ectropion in elderly patients as well as infants with lamellar ichthyosis. In these cases the HA was injected and left in place to dissolve itself.  Our case is the first report of a HA with high G’ properties injected directly under the skin followed by complete dissolution with hyaluronidase once the tissue expansion took place.
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